141135
2,3-Dicyanohydroquinone
98%
Synonym(s):
2,3-Dicyano-1,4-hydroquinone, 3,6-Dihydroxyphthalonitrile, DCH
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About This Item
Linear Formula:
(NC)2C6H2-1,4-(OH)2
CAS Number:
Molecular Weight:
160.13
Beilstein:
2101249
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Assay
98%
form
powder
mp
>230 °C (dec.) (lit.)
SMILES string
Oc1ccc(O)c(C#N)c1C#N
InChI
1S/C8H4N2O2/c9-3-5-6(4-10)8(12)2-1-7(5)11/h1-2,11-12H
InChI key
MPAIWVOBMLSHQA-UHFFFAOYSA-N
Related Categories
Application
2,3-Dicyanohydroquinone was used in the synthesis of phthalonitrile-3,6-ditriflate. It is a fluorescent dye and was used in determination of intracellular pH and calcium in avian neural crest cells.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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P E van Erp et al.
Cytometry, 12(2), 127-132 (1991-01-01)
In this study we describe a method to measure intracellular pH in cultured human keratinocytes using flow cytometry. Keratinocytes pose a technical problem because the population is heterogeneous with respect to size and metabolic activity (nonspecific esterase activity), resulting in
E D Wieder et al.
Cytometry, 14(8), 916-921 (1993-11-01)
The new intracellular pH (pH(i)) dye carboxy-seminaphthorhodafluor (SNARF-1) was compared to the established dye 2,3-dicyanohydroquinone (DCH) using flow cytometry. Both dyes give high-resolution pH(i) measurements. SNARF-1 remains trapped within cells much longer than DCH, so that pH(i) can be monitored
J I Gillespie et al.
The Journal of physiology, 405, 385-395 (1988-11-01)
1. Measurements of intracellular pH (pHi) have been made using the fluorescent dye dicyano-hydroquinone (DCH) in somites isolated from 2-day-old chick embryos. Measurements of pHi, from freshly dissected somites, gave values of 7.18 +/- 0.02 (mean +/- S.D., n =
Fast intracellular pH determination in single cells by flow-cytometry.
G Valet et al.
Die Naturwissenschaften, 68(5), 265-266 (1981-05-01)
D J Maas et al.
The Review of scientific instruments, 86(10), 103702-103702 (2015-11-02)
With lithographic patterning dimensions decreasing well below 50 nm, it is of high importance to understand metrology at such small scales. This paper presents results obtained from dense arrays of contact holes (CHs) with various Critical Dimension (CD) between 15
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