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89862

Sigma-Aldrich

β-1,3-Glucan from Euglena gracilis

Synonym(s):

Paramylon

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About This Item

CAS Number:
9051-97-2
MDL number:
MFCD00466918
UNSPSC Code:
12352201
PubChem Substance ID:
329769552
NACRES:
NA.25
Pricing and availability is not currently available.

biological source

(Euglena gracilis)

form

powder

color

white to faint beige

SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O[C@@H]3O[C@@H]([C@H](C[C@H]3O)O)CO)O)O[C@H]2[C@@H]([C@H](OC[C@@H]2O)CO)O

InChI

1S/C18H32O14/c19-2-9-6(22)1-7(23)17(29-9)32-16-13(26)11(4-21)30-18(14(16)27)31-15-8(24)5-28-10(3-20)12(15)25/h6-27H,1-5H2/t6-,7+,8-,9+,10+,11+,12+,13+,14+,15+,16-,17-,18-/m0/s1

InChI key

SPMCUTIDVYCGCK-IIIGWGBSSA-N

Related Categories

General description

The molecule consists of a linear chain of glucose units without any branching.

Application

β-1,3-Glucan from Euglena gracilis may be compared with other β-1,3-glucans and their derivatives to study mechanisms of protection of DNA from oxidative lesions. β-1,3-Glucan from Euglena gracilis may be used as a substrate to identify, differentiate and characterize glucanase(s).

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM5097
BCCL6360
BCCK5480
BCCH1918
BCCJ8314

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Xiaoli Zheng et al.
Developmental and comparative immunology, 36(3), 602-609 (2011-11-09)
Pattern recognition proteins, which form part of the innate immune system, initiate host defense reactions in response to pathogen surface molecules. The pattern recognition protein β-1,3-glucan recognition protein (βGRP) binds to β-1,3-glucan on fungal surfaces to mediate melanization via the
V Blättel et al.
Applied and environmental microbiology, 77(3), 983-990 (2010-12-21)
During vinification microbial activities can spoil wine quality. As the wine-related lactic acid bacterium Pediococcus parvulus is able to produce slimes consisting of a β-1,3-glucan, must and wine filtration can be difficult or impossible. In addition, the metabolic activities of
Frédéric Lamoth et al.
Eukaryotic cell, 11(11), 1324-1332 (2012-07-24)
Heat shock protein 90 (Hsp90) is a eukaryotic molecular chaperone. Its involvement in the resistance of Candida albicans to azole and echinocandin antifungals is well established. However, little is known about Hsp90's function in the filamentous fungal pathogen Aspergillus fumigatus.
Jakob Skov et al.
Fish & shellfish immunology, 33(1), 111-120 (2012-05-03)
Potential immunostimulatory effects of orally administered β-glucan were investigated in combination with immersion vaccination against enteric redmouth disease caused by Yersinia ruckeri in rainbow trout (Oncorhynchus mykiss). A linear, unbranched and pure (purity ≥98%) β-1,3-glucan (syn. paramylon) from the alga
Harrison B Taylor et al.
Nutrients, 12(8) (2020-07-29)
Previously, we have shown that oral administration of yeast derived β-1,3/1,6-d-glucan enhances immune regulation and alters the composition of the gut microbiota. However, it is not known if other structurally distinct β-glucans have similar properties. Here, using C57BL/6 mice, we
View All Related Papers

Questions

1–4 of 4 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Hi, I wanted to ask what is the best way to dissolve beta 1,3-glucan (product number 89862). Many thanks in advance, Kind regards Marilena

    1 answer

    1. Solubility is not a routine assay that is performed and quality is guaranteed on this product. If you require further details on the solubility of paramylon in specific solvents it is recommended to refer to scientific literature and conduct a specific solubility test. A potential solvent to test may be a dilute alkaline solution such as 0.5 M NaOH.

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  4. what is the molecular weight?

    1 answer

    1. The molecular weight of this product is approximately 500,000 Da, as mentioned in the General Description section of the product page.

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