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387A

Sigma-Aldrich

Leukocyte Acid Phosphatase (TRAP) Kit

Kit formulated with all liquid reagents

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About This Item

UNSPSC Code:
12352106
eCl@ss:
42010102
NACRES:
NA.47

shelf life

Expiry date on the label.

IVD

for in vitro diagnostic use

application(s)

hematology
histology

shipped in

wet ice

storage temp.

2-8°C

Principle

Peripheral blood or bone marrow preparations are fixed to a microscope slide. The resulting film is incubated in a solution of Naphthol AS-BI phosphoric acid and freshly diazotized Fast Garnet GBC. Kit is used to demonstrate acid phosphatase and tartrate resistant acid phosphatase (TRAP) in blood, bone marrow and tissue touch preparations.

Kit Components Only

Product No.
Description

  • Hematoxylin Solution, Gill No. 3 (kit only) 50 mL

Kit Components Also Available Separately

Product No.
Description
SDS

  • 3863Acetate Solution, 2.5 M, pH 5.2 50 mLSDS

  • 915Citrate Solution, pH 3.6±0.1 (25 °C), 27 mM 50 mLSDS

  • 3872Fast Garnet GBC Base Solution 10 mLSDS

  • 3871Naphthol AS-BI Phosphoric Acid Solution 10 mLSDS

  • 914Sodium nitrite solution 10 mLSDS

  • 3873Tartrate Solution 10 mLSDS

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B - STOT RE 2 Oral

Target Organs

Kidney

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3


Certificates of Analysis (COA)

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Yun Zhang et al.
Biological & pharmaceutical bulletin, 39(12), 2028-2035 (2016-12-03)
Osteolysis induced by chronic Gram-negative bacterial infection underlies many bone diseases such as osteomyelitis, septic arthritis, and periodontitis. Drugs that inhibit lipopolysaccharide (LPS)-induced osteolysis are critically needed for the prevention of bone destruction in infective bone diseases. In this study
Jihai Wang et al.
Frontiers in pharmacology, 9, 64-64 (2018-02-24)
Lipopolysaccharide (LPS) can induce bone loss by stimulating bone resorption. Natural compounds have great potential for the treatment of osteolytic bone diseases. Magnesium lithospermate B (MLB) plays an important role in protecting against oxidative damage and also has potential anti-inflammatory
L Wei et al.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 25(8), 2089-2096 (2014-05-09)
Recently, the use of the pharmacological agent strontium ranelate has come to prominence for the treatment of osteoporosis. While much investigation is focused on preventing disease progression, here we fabricate strontium-containing scaffolds and show that they enhance bone defect healing
Zhongbo Liu et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 33(1), 123-136 (2017-09-14)
Hepatic osteodystrophy is multifactorial in its pathogenesis. Numerous studies have shown that impairments of the hepatic growth hormone/insulin-like growth factor-1 axis (GH/IGF-1) are common in patients with non-alcoholic fatty liver disease, chronic viral hepatitis, liver cirrhosis, and chronic cholestatic liver
Robert A Britton et al.
Journal of cellular physiology, 229(11), 1822-1830 (2014-03-29)
Estrogen deficiency is a major risk factor for osteoporosis that is associated with bone inflammation and resorption. Half of women over the age of 50 will experience an osteoporosis related fracture in their lifetime, thus novel therapies are needed to

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