P0657

Phthaldialdehyde

suitable for HPLC fluorimetric detection of amino acids, ≥99% (HPLC), powder or crystals

• Synonym(s): o-Phthalaldehyde, o-Phthalic dicarboxaldehyde, Benzene-1,2-dicarboxaldehyde, OPA
• Empirical Formula (Hill Notation): C₈H₆O₂
• CAS Number: 643-79-8
• Molecular Weight: 134.13
• Beilstein: 878317
• EC Number: 211-402-2
• MDL number: MFCD00003335
• UNSPSC Code: 12352201
• PubChem Substance ID: 24898119
• NACRES: NA.21

Properties

• Quality Level: 200
• Assay: ≥99% (HPLC)
• form: powder or crystals
• technique(s): HPLC: suitable
• color: white to light yellow
• mp: 55-58 °C
• suitability: suitable for HPLC fluorimetric detection of amino acids
• storage temp.: 2-8°C
• SMILES string: O=Cc1ccccc1C=O
• InChI: 1S/C8H6O2/c9-5-7-3-1-2-4-8(7)6-10/h1-6H
• InChI key: ZWLUXSQADUDCSB-UHFFFAOYSA-N

Description

Application

Phthaldialdehyde has been used:

• in the preparation of O-phthaldialdehyde reagent for analysing gentamycin content[1]
• in the preparation of reagent for determining the degree of hydrolysis of milk proteins[2]
• in the measurement of free amino acids of milk samples by O-phthaldialdehyde/N-acetyl-L-cysteine (OPA/NAC) assay[3]
• in the derivatization of putrescine samples[4]

Biochem/physiol Actions

Phthaldialdehyde can be used for the pre-column derivatization of amino acids for high-performance liquid chromatography (HPLC) separation. It may also be used for flow cytometric measurements of protein thiol groups.

Safety Information

• Pictograms: GHS06,GHS05,GHS09
• Signal Word: Danger
• Hazard Statements: H301,H314,H317,H335,H410
• Precautionary Statements: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 269.6 °F - closed cup
• Flash Point(C): 132 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves