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B1385

Supelco

Butoxamine hydrochloride

analytical standard, for drug analysis, mixture of diastereomers

Synonym(s):

α-(1-[t-Butylamino]ethyl)-2,5-dimethoxybenzyl alcohol

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About This Item

Empirical Formula (Hill Notation):
C15H25NO3 · HCl
CAS Number:
Molecular Weight:
303.82
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard, for drug analysis

Quality Level

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.COc1ccc(OC)c(c1)C(O)C(C)NC(C)(C)C

InChI

1S/C15H25NO3.ClH/c1-10(16-15(2,3)4)14(17)12-9-11(18-5)7-8-13(12)19-6;/h7-10,14,16-17H,1-6H3;1H

InChI key

URPAECSKKQLCII-UHFFFAOYSA-N

General description

Butoxamine hydrochloride is a β-andrenoceptor antagonist, which shows β2-selectivity.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Claudio Molinari et al.
Endocrinology, 148(8), 4080-4090 (2007-04-28)
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BioMed research international, 2020, 3214186-3214186 (2020-05-29)
Adrenaline quickly inhibits the release of histamine from mast cells. Besides β2-adrenergic receptors, several in vitro studies also indicate the involvement of α-adrenergic receptors in the process of exocytosis. Since exocytosis in mast cells can be detected electrophysiologically by the
Jiayin Lu et al.
International journal of molecular sciences, 22(3) (2021-02-06)
Restraint stress causes various maternal diseases during pregnancy. β2-Adrenergic receptor (β2-AR) and Forkhead transcription factor class O 1 (FOXO1) are critical factors not only in stress, but also in reproduction. However, the role of FOXO1 in restraint stress, causing changes
Nan Yang et al.
Respiratory research, 22(1), 65-65 (2021-02-25)
Airway inflammation is a key feature of chronic obstructive pulmonary disease (COPD) and inhaled corticosteroids (ICS) remain the main treatment for airway inflammation. Studies have noted the increased efficacy of ICS and long-acting beta 2 agonist (LABA) combination therapy in
Cardiovascular teratogenicity of terbutaline and ritodrine in the chick embryo
Lenselink R.D, et al.
American Journal of Obstetrics and Gynecology, 171(2), 501-506 (1994)

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