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90151

Supelco

17β-Hydroxy-17-methylandrosta-1,4-dien-3-one

analytical standard

Synonym(s):

1-Dehydro-17α-methyltestosterone, Dianabol, Methandienone, Methandrostenolone

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About This Item

Empirical Formula (Hill Notation):
C20H28O2
CAS Number:
Molecular Weight:
300.44
Beilstein:
2056255
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥97.0% (HPLC)

optical activity

[α]1.15/D -0.5±0.5° in chloroform

shelf life

limited shelf life, expiry date on the label

drug control

USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

functional group

ketone

storage temp.

2-8°C

SMILES string

C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C20H28O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h6,9,12,15-17,22H,4-5,7-8,10-11H2,1-3H3/t15-,16+,17+,18+,19+,20+/m1/s1

InChI key

XWALNWXLMVGSFR-HLXURNFRSA-N

Gene Information

human ... AR(367)

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General description

17β-hydroxy-17-methylandrosta-1,4-dien-3-one is an androgenic anabolic steroid.

Application

17β-hydroxy-17-methylandrosta-1,4-dien-3-one may be used as a reference standard in the determination of 17β-hydroxy-17-methylandrosta-1,4-dien-3-one in urine samples, using by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Comparative study of matrices for their use in the rapid screening of anabolic steroids by matrix?assisted laser desorption/ionisation time?of?flight mass spectrometry
Galesio.M, et al.
Rapid Communications in Mass Spectrometry, 23, 1783-1791 (2009)
Linda L Ahonen et al.
Rapid communications in mass spectrometry : RCM, 24(7), 958-964 (2010-03-09)
We examined the feasibility of capillary liquid chromatography/microchip atmospheric pressure photoionization tandem mass spectrometry (capLC/microAPPI-MS/MS) for the analysis of anabolic steroids in human urine. The urine samples were pretreated by enzymatic hydrolysis (with beta-glucuronidase from Helix pomatia), and the compounds
Yun Wang et al.
International journal of biological macromolecules, 49(3), 428-432 (2011-06-15)
The development of a chitosan-supported immunoaffinity chromatography (IAC) column and its application to the selective extraction of methandrostenolone (MA) from food and feed samples were described in this paper. Using hybridoma technique, a monoclonal antibody (mAb) against MA was produced.
Alaa Alhadad et al.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 16(2), 228-231 (2008-11-04)
We present the case of a 19-year-old male athlete with protein C deficiency who developed proximal deep venous thrombosis and pulmonary embolism while abusing anabolic-androgenic steroids. Anabolic-androgenic steroids have been reported to have anticoagulatory and profibrinolytic effects in patients with
Leen Lootens et al.
Clinical chemistry, 55(10), 1783-1793 (2009-08-01)
Adequate detection of designer steroids in the urine of athletes is still a challenge in doping control analysis and requires knowledge of steroid metabolism. In this study we investigated whether uPA(+/+)-SCID mice carrying functional primary human hepatocytes in their liver

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