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32802

Supelco

Triclabendazole

VETRANAL®, analytical standard

Synonym(s):

5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole

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About This Item

Empirical Formula (Hill Notation):
C14H9Cl3N2OS
CAS Number:
Molecular Weight:
359.66
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

CSc1nc2cc(Cl)c(Oc3cccc(Cl)c3Cl)cc2[nH]1

InChI

1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)

InChI key

NQPDXQQQCQDHHW-UHFFFAOYSA-N

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General description

Chemical structure: benzimidazole

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ali Farahnak et al.
Acta medica Iranica, 50(3), 164-168 (2012-03-16)
Fascioliasis is an endemic disease in Iran and triclabendazole (TCBZ) is using for treatment of domestic animals and infected people. Excretory-secretory products (ESP) play an important role in the host biochemical defense by means of activities of detoxifying and antioxidant
Access to medicines for orphan diseases: experience in the management of a case of Fasciola hepatica in Mumbai, Maharashtra, India.
U M Thatte et al.
The National medical journal of India, 25(4), 234-235 (2013-01-03)
Michaela Haider et al.
Veterinary parasitology, 187(3-4), 445-451 (2012-03-03)
During the past decade, Fascioloides magna, the large American liver fluke, has spread within free-living deer in wetlands of the Danube in Lower Austria. The aim of this study was to determine the current infection rates with F. magna and
Confirmation of triclabendazole resistance in liver fluke in the UK.
Danielle Gordon et al.
The Veterinary record, 171(6), 159-160 (2012-08-15)
Michelle Whelan et al.
Journal of chromatography. A, 1275, 41-47 (2013-01-08)
Triclabendazole is the only anthelmintic drug, which is active against immature, mature and adult stages of fluke. The objective of this work was to develop an analytical method to quantify and confirm the presence of triclabendazole residues around the MRL.

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