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Eprinomectin

PESTANAL®, analytical standard, mixture of isomers

Synonym(s):

(4′’R)-4″-(Acetylamino)-4″-deoxy-avermectin B1

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About This Item

Empirical Formula (Hill Notation):
C50H75NO14
CAS Number:
Molecular Weight:
914.13
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

quality

mixture of isomers

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

storage temp.

−20°C

SMILES string

C[C@H]1[C@H](NC(C)=O)[C@@H](OC)C[C@H](O[C@H]2[C@H](C)O[C@@H](O[C@H](/C(C)=C/C[C@]3([H])C[C@H]4C[C@@]5(O[C@@]([R])([H])[C@@H](C)C=C5)O3)[C@@H](C)/C=C/C=C(CO6)/[C@@]([C@@]6([H])[C@H](O)C(C)=C7)(O)[C@]7([H])C(O4)=O)C[C@@H]2OC)O1.CCC.CCCC

InChI

1S/C49H73NO14/c1-25(2)43-28(5)17-18-48(64-43)23-35-20-34(63-48)16-15-27(4)44(26(3)13-12-14-33-24-57-46-42(52)29(6)19-36(47(53)60-35)49(33,46)54)61-40-22-38(56-11)45(31(8)59-40)62-39-21-37(55-10)41(30(7)58-39)50-32(9)51/h12-15,17-19,25-26,28,30-31,34-46,52,54H,16,20-24H2,1-11H3,(H,50,51)/b13-12-,27-15-,33-14-/t26-,28-,30-,31-,34+,35-,36-,37+,38-,39-,40-,41+,42+,43+,44-,45+,46+,48+,49+/m0/s1

InChI key

WPNHOHPRXXCPRA-TVXIRPTOSA-N

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General description

Eprinomectin is a second generation macrocyclic lactone, used as a topical endectocide which is active both against endoparasites and ectoparasites for all cattle, including lactating dairy cows.

Application

Eprinomectin has been used as a standard for the determination of pesticide residues in soil samples by the on-line solid-phase extraction-ultra high performance liquid chromatography-tandem mass spectrometry. It may also be used to examine the presence of any veterinary drug residues in the bulk milk tank.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Milk quality parameters associated with the occurrence of veterinary drug residues in bulk tank milk.
Picinin L C A, et al.
Scientia Agricola, 74(3), 195-202 (2017)
On-line solid-phase extraction-ultra high performance liquid chromatography-tandem mass spectrometry for the determination of avermectins and milbemycin in soils.
de Oliveira Ferreira F, et al
Journal of Chromatography A, 1471, 118-125 (2016)
Eprinomectin: a novel avermectin for use as a topical endectocide for cattle.
Shoop W L, et al.
International Journal For Parasitology, 26(11), 1237-1242 (1996)
Steffen Rehbein et al.
Parasitology research, 111(3), 1343-1347 (2012-05-29)
A study was conducted to confirm the efficacy of topical eprinomectin against nematodes and to evaluate the pharmacokinetics in cattle prevented from having physical contact with other cattle and from self-grooming. Sixteen male Brown Swiss calves were infected with larvae
Johannes Charlier et al.
Preventive veterinary medicine, 93(2-3), 147-152 (2009-11-17)
The aim of this study was to explore whether anti-Ostertagia ostertagi antibody levels measured by ELISA in individual milk samples hold promise as a decision parameter for either herd-level decisions or selective anthelmintic treatments by investigating (1) the relationship between

Protocols

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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