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8.51014
Fmoc-OSu
≥99.0% (HPLC), for peptide synthesis, Novabiochem®
Synonym(s):
Fmoc-OSu, FMOC-ONSu, N-(9H-Fluoren-9-ylmethoxycarbonyloxy)succinimide, N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 9-Fluorenylmethyl-succinimidyl carbonate
About This Item
Recommended Products
Product Name
Fmoc-OSu, Novabiochem®
Quality Level
product line
Novabiochem®
Assay
≥99.0% (HPLC)
form
powder
manufacturer/tradename
Novabiochem®
mp
145-148 °C
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
2-8°C
SMILES string
N4(C(=O)CCC4=O)OC(=O)OCC1c2c(cccc2)c3c1cccc3
InChI
1S/C19H15NO5/c21-17-9-10-18(22)20(17)25-19(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2
InChI key
WMSUFWLPZLCIHP-UHFFFAOYSA-N
Related Categories
General description
Literature references
[1] A. Paquet (1982) Can. J. Chem., 60, 976.
[2] L. Lapatsanis, et al. (1983) Synthesis, 671.
[3] G. F. Sigler, et al. (1983) Biopolymers, 22, 2157.
Application
- Sequence-defined positioning of amine and amide residues to control catechol driven wet adhesion: This study uses Fmoc-OSu for selective functionalization of amines, demonstrating its role in synthesizing complex molecules with specific adhesive properties (Fischer et al., 2020).
- Fmoc-OASUD: A new reagent for the preparation of Fmoc-amino acids free from impurities resulting from Lossen rearrangement: Discusses the development of Fmoc-OASUD as a superior alternative to Fmoc-OSu, reducing impurities in peptide synthesis processes (Rao et al., 2016).
Linkage
Analysis Note
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Legal Information
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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