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E32754

Sigma-Aldrich

4,6-O-Ethylidene-α-D-glucose

Synonym(s):

4,6-O-Ethylidene α-D-glucopyranose, Ethylidene glucose, NSC 89726

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About This Item

Empirical Formula (Hill Notation):
C8H14O6
CAS Number:
13224-99-2
Molecular Weight:
206.19
EC Number:
236-198-2
MDL number:
MFCD00006820
UNSPSC Code:
12352200
PubChem Substance ID:
24894503
NACRES:
NA.22

mp

168-170 °C (lit.)

SMILES string

CC1OC[C@H]2O[C@H](O)[C@H](O)[C@@H](O)[C@@H]2O1

InChI

1S/C8H14O6/c1-3-12-2-4-7(13-3)5(9)6(10)8(11)14-4/h3-11H,2H2,1H3/t3?,4-,5-,6-,7-,8+/m1/s1

InChI key

VZPBLPQAMPVTFO-NKWOADHPSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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J Kawada et al.
Molecular and cellular endocrinology, 62(2), 153-159 (1989-04-01)
4,6-O-Ethylidene glucose (ethylidene glucose), a specific inhibitor at the outer surface of a glucose transporter in the cell membranes, substituted analogue of streptozotocin was newly synthesized. This compound did not induce diabetes in rats and also did not show cytotoxic
A Janoshazi et al.
The Journal of membrane biology, 123(3), 191-207 (1991-09-01)
We have previously shown that the human red cell glucose transport protein and the anion exchange protein, band 3, are in close enough contact that information can be transmitted from the glucose transport protein to band 3. The present experiments
A F Gibbs et al.
The Biochemical journal, 256(2), 421-427 (1988-12-01)
Tryptic digestion has been used to investigate the conformational changes associated with substrate translocation by the human erythrocyte glucose transporter. The effects of substrates and inhibitors of transport on the rates of tryptic cleavage at the cytoplasmic surface of the
M Wellner et al.
FEBS letters, 370(1-2), 19-22 (1995-08-14)
Two triple cysteine mutants containing Cys-less N- or C-terminal halves and the Cys-less GLUT1 were generated by site-directed mutagenesis. Following expression in Xenopus oocytes, the intrinsic transport activities of the multiple cysteine mutants were slightly decreased when either the cysteine
J Kawada et al.
The Journal of endocrinology, 112(3), 375-378 (1987-03-01)
Ethylidene glucose (4,6-O-ethylidene glucose; EG) is known to bind the outer surface of the glucose transporter in the membranes of human erythrocytes and other mammalian cells. If a glucose transport system is present on pancreatic beta cells and recognizes the
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