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84172

Sigma-Aldrich

Salicylaldoxime

≥98.0% (NT)

Synonym(s):

2-Hydroxybenzaldehyde oxime

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About This Item

Linear Formula:
2-(HO)C6H4CH=NOH
CAS Number:
94-67-7
Molecular Weight:
137.14
Beilstein:
1859881
EC Number:
202-353-8
MDL number:
MFCD00002120
UNSPSC Code:
12352100
PubChem Substance ID:
57652990
NACRES:
NA.22

Quality Level

200

Assay

≥98.0% (NT)

form

crystals

mp

57-59 °C
59-61 °C (lit.)

functional group

amine
oxime

SMILES string

O\N=C\c1ccccc1O

InChI

1S/C7H7NO2/c9-7-4-2-1-3-6(7)5-8-10/h1-5,9-10H/b8-5+

InChI key

ORIHZIZPTZTNCU-VMPITWQZSA-N

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Application


  • Novel uncharged triazole salicylaldoxime derivatives as potential acetylcholinesterase reactivators: This research focuses on the synthesis and evaluation of novel salicylaldoxime derivatives, aimed at reactivating acetylcholinesterase inhibited by nerve agents (MH Baghersad, A Habibi, 2023).

  • Selectivity of Salicylaldoxime and its Derivatives: This study utilizes Density Functional Theory (DFT) to examine the selectivity and effectiveness of salicylaldoxime derivatives in various chemical applications (B Tuzun, 2014).

  • Synthesis and Spectroscopic study of Pd(II)-Salicylaldoxime complexes with amine ligands: This paper presents the synthesis and characterization of new Pd(II) complexes with salicylaldoxime, exploring their potential uses in catalysis and material science (EN Al_Sabawi et al., 2021).

Other Notes

Reagent for the spectrophotometric determination of Cu(II), Fe (III), Mo(VI) and Ni(II); a review

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM2937
BCCK3369
BCCJ5206
BCCJ4766
BCCG1083

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Tiziano Tuccinardi et al.
Bioorganic & medicinal chemistry, 21(6), 1511-1515 (2012-09-29)
New compounds containing a novel zinc binding group (salicylaldoxime system) were identified as effective inhibitors of carbonic anhydrases (CAs). This structural motif seems to bind the catalytic zinc ion of CAs, revealing itself as a new valid alternative to the
Peter A Wood et al.
Acta crystallographica. Section B, Structural science, 62(Pt 6), 1099-1111 (2006-11-17)
The effect of pressure on the crystal structure of salicylaldoxime has been investigated. The ambient-pressure phase (salicylaldoxime-I) consists of pairs of molecules interacting through oximic OH...O hydrogen bonds; taken with phenolic OH...N intramolecular hydrogen bonds, these dimers form a pseudo-macrocycle
Anna Tobiasz et al.
Talanta, 96, 82-88 (2012-07-24)
The paper presents application of a new resin dedicated to copper(II) flow-injection on-line preconcentration prior its flame atomic absorption spectrometric (FAAS) determination. The new sorbent, obtained by suspension polymerization technique, was styrene-divinylbenzene copolymer modified with 5-dodecylsalicylaldoxime-copper(II) complex. In flow mode
Chrysa Kozoni et al.
Dalton transactions (Cambridge, England : 2003), 39(34), 7943-7950 (2010-08-04)
The reaction of MnCl(2).4H(2)O with DL-valine (Val) in MeOH in the presence of Et-saoH(2) (2-hydroxypropiophenone oxime) and NEt(4)OH forms the complex [Mn(III)(3)Mn(IV)(2)O(2)(CH(3)O)(Et-sao)(6)(Val)].Val.1.5H(2)O (1.Val.1.5H(2)O) in very good yields. A similar reaction of MnCl(2).4H(2)O with Glycine (Gly) in MeOH in the presence
Laura Adamovicz et al.
Journal of experimental zoology. Part A, Ecological and integrative physiology, 333(10), 720-731 (2020-10-20)
Eastern (Terrapene carolina carolina) and ornate (Terrapene ornata ornata) box turtles have robust plasma antibacterial activity, however, the mechanism behind this activity is unknown. We used sheep red blood cell (SRBC) hemolysis assays, mannan-affinity chromatography, sodium dodecyl sulfate polyacrylamide gel
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