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Key Documents

47060

Sigma-Aldrich

Fluoride on polymer support

extent of labeling: ~3.0 mmol/g F- loading

Synonym(s):

Amberlite™ IRA 900 F--form

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About This Item

UNSPSC Code:
12352128
PubChem Substance ID:
24870668
NACRES:
NA.22
Pricing and availability is not currently available.

reaction suitability

reaction type: solution phase peptide synthesis

Quality Level

100

extent of labeling

~3.0 mmol/g F- loading

impurities

≤0.1 mmol/g Cl- (resin)
15-20% water

Related Categories

Other Notes

For a convenient synthesis of alkyl fluorides from alkyl halides or sulfonates [1]; Heterogenous basic catalyst for C- and O-alkylations, sulfenylations and Michael additions [2]; deprotection of silyl ethers[3]

Legal Information

Amberlite is a trademark of DuPont de Nemours, Inc.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBZ9644
BCBS9216V
BCBL1596V
BCBG6209V
1436939V

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S. Colonna et al.
Journal of the Chemical Society. Perkin Transactions 1, 2248-2248 (1979)
C. Cardillo et al.
Chemistry & Industry, 643-643 (1983)
G. Cardillo et al.
The Journal of Organic Chemistry, 49, 701-701 (1984)
Elena Chiurchiù et al.
Molecules (Basel, Switzerland), 24(24) (2019-12-19)
Highly functionalized furans are the key scaffolds of many pharmaceuticals and bioactive natural products. Herein, we disclose a new fruitful synthesis of polyfunctionalized furans starting from β-nitroenones and α-functionalized ketones. The protocol involves two steps promoted by solid supported species

Questions

  1. Is there any special way to dry or activate this product?

    1 answer

    1. Here is a Technical Fact sheet from Dupont, that refers to the regeneration/activation conditions: https://www.dupont.com/content/dam/dupont/amer/us/en/water-solutions/public/documents/en/IER-Recommended-Operating-Conditions-Separate-Beds-TechFact-45-D01131-en.pdf

      Additionally, for Amberlite™ IRA 900 F, which is a strong base anion exchange resin, the regeneration process would typically involve using a sodium hydroxide solution to restore its exchange capacity. The exact concentration of the regenerating solution, the flow rate, the temperature, and the contact time are important parameters that need to be optimized for efficient regeneration. These parameters can vary depending on the specific application, the composition of the water or solution being treated, and the degree of exhaustion of the resin.

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