T7790
Tyrphostin 63
≥98%
Synonym(s):
4-Hydroxybenzyl malononitrile
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About This Item
Empirical Formula (Hill Notation):
C10H8N2O
CAS Number:
Molecular Weight:
172.18
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Pricing and availability is not currently available.
Assay
≥98%
potency
6500 μM IC50 (negative control)
solubility
DMSO: soluble
storage temp.
2-8°C
SMILES string
Oc1ccc(CC(C#N)C#N)cc1
InChI
1S/C10H8N2O/c11-6-9(7-12)5-8-1-3-10(13)4-2-8/h1-4,9,13H,5H2
InChI key
PDRLQWJJFLVIRC-UHFFFAOYSA-N
Biochem/physiol Actions
EGFR tyrosine kinase inhibitor.
Preparation Note
Tyrphostins are soluble in DMSO. Although the presence of water in the solution may accelerate hydrolysis, frozen solutions in DMSO should still be stable for months.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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