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SRP5242

Sigma-Aldrich

ERK5, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

BMK1, ERK4, MAPK7, PRKM7

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About This Item

CAS Number:
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

product line

PRECISIO® Kinase

Assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

9.4-12.7 nmol/min·mg

mol wt

~132 kDa

NCBI accession no.

application(s)

cell analysis

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... MAPK7(5598)

Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Role of MAPK7 in cell proliferation and metastasis in ovarian cancer
Jinhua D
International Journal of Clinical and Experimental Pathology (2015)
MAPK7 gene controls proliferation, migration and cell invasion in osteosarcoma.
Tesser-Gamba F
Molecular Carcinogenesis (2016)
C1q-TNF-related protein-9 promotes cardiac hypertrophy and failure
Mahesh Appari
Circulation Research (2016)
ERK5 Mediated Signalling in Diabetic Retinopathy
Yuexiu Wu
Medical Hypotheses (2015)
Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinoma
Paul R. Gavine
BMC Cancer (2015)

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