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SML2720

Sigma-Aldrich

Miriplatin

>97.5% (Pt analysis)

Synonym(s):

Cyclohexane-(1R,2R)-diamineplatinum(II) dimyristate, MPT, SM-11355

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₹7,936.50
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Estimated to ship on06 June 2025Details

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10 MG
₹7,936.50
50 MG
₹32,067.90

About This Item

Empirical Formula (Hill Notation):
C34H68N2O4Pt
CAS Number:
141977-79-9
Molecular Weight:
763.99
UNSPSC Code:
12352200
NACRES:
NA.77

₹7,936.50

Estimated to ship on06 June 2025Details

Request a Bulk Order

Quality Level

100

Assay

>97.5% (Pt analysis)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCC(O[Pt]1(N[C@@H]2CCCC[C@H]2N1)OC(CCCCCCCCCCCCC)=O)=O

InChI

1S/2C14H28O2.C6H12N2.Pt/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16;7-5-3-1-2-4-6(5)8;/h2*2-13H2,1H3,(H,15,16);5-8H,1-4H2;/q;;-2;+4/p-2/t;;5-,6-;/m..1./s1

InChI key

DTRJSYSQELJDAW-BLUNCNMSSA-L

Biochem/physiol Actions

Miriplatin (SM-11355) is a platinum (II) complex-based anti-neoplastic agent with increased lipophilicity than its family members cisplatin and carboplatin.
Platinum (II) complex-based anti-neoplastic agent with increased lipophilicity than cisplatin and carboplatin.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Kenji Ikeda et al.
Hepatology research : the official journal of the Japan Society of Hepatology, 47(7), 632-640 (2016-08-04)
The effect of transcatheter arterial chemoembolization (TACE) is not necessarily sufficient in patients with multiple hepatocellular carcinoma (HCC). We evaluated the antitumor activity and adverse events of TACE using warmed miriplatin suspension for multiple HCC. Seventy patients with multiple HCC
Toru Ishikawa et al.
Molecular and clinical oncology, 5(5), 511-516 (2016-11-25)
Transcatheter arterial chemoembolization (TACE) is the standard therapy for Barcelona Clinic Liver Cancer (BCLC) classification intermediate stage B hepatocellular carcinoma (HCC). However, other transcatheter methods, such as transcatheter arterial infusion (TAI), also play an important role in the treatment of
Shan Liu et al.
Journal of pharmaceutical sciences, 105(1), 78-87 (2016-02-09)
Because of the insolubility of miriplatin in water, miriplatin and lipiodol suspension is the sole formulation of miriplatin approved in Japan to treat hepatocellular carcinoma by transcatheter arterial chemoembolization. Until now, there have been no reports of other pharmaceutical formulations

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