Skip to Content
Merck
All Photos(1)

Key Documents

SML1752

Sigma-Aldrich

LF3

≥98% (HPLC)

Synonym(s):

N-[4-(Aminosulfonyl)phenyl]-4-(3-phenyl-2-propen-1-yl)-1-piperazinecarbothioamide

Sign Into View Organizational & Contract Pricing

Select a Size

5 MG
₹12,156.48

₹12,156.48


Estimated to ship on28 April 2025Details



Select a Size

Change View
5 MG
₹12,156.48

About This Item

Empirical Formula (Hill Notation):
C20H24N4O2S2
CAS Number:
Molecular Weight:
416.56
UNSPSC Code:
12352200
NACRES:
NA.77

₹12,156.48


Estimated to ship on28 April 2025Details


Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

S=C(NC1=CC=C(S(N)(=O)=O)C=C1)N2CCN(C/C=C/C3=CC=CC=C3)CC2

InChI

1S/C20H24N4O2S2/c21-28(25,26)19-10-8-18(9-11-19)22-20(27)24-15-13-23(14-16-24)12-4-7-17-5-2-1-3-6-17/h1-11H,12-16H2,(H,22,27)(H2,21,25,26)/b7-4+

InChI key

ZUQIFHLBPBLRRM-QPJJXVBHSA-N

Biochem/physiol Actions

LF3 is a potent inhibitor of Wnt/β-catenin signaling that suppresses cancer cells motility, cell-cycle progression, and the overexpression of Wnt target genes.
LF3 is a potent inhibitor of Wnt/β-catenin signaling that suppresses cancer cells motility, cell-cycle progression, and the overexpression of Wnt target genes. LF3 is a potent and specific antagonist of the interaction between β-catenin and the transcription factor TCF4. LF3 blocks self-renewal of cancer stem cells.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service