SCP0073
Caspase 1 Substrate (ICE), fluorogenic
≥95% (HPLC), lyophilized
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About This Item
Empirical Formula (Hill Notation):
C35H41N5O12
Molecular Weight:
723.73
UNSPSC Code:
12352202
NACRES:
NA.32
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product name
Caspase 1 Substrate (ICE), fluorogenic,
Assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥75%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Ac-Tyr-Glu-Val-Asp-AMC
Application
Caspase 1 is a cysteine protease activator of inflammatory processes which may be detected using a variety of chromogenic and fluorogenic peptide substrates build around the YEVD (Tyr-Glu-Val-Asp) sequence. These substrates include: Ac-YEVD-pNa (Ac-Tyr-Glu-Val-Asp-p-nitroanalide), chromogenic and Ac-YEVD-AMC (Ac-Tyr-Glu-Val-Asp-7-amino-4-methylcoumarin), fluorogenic.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Cell death and differentiation, 14(1), 10-22 (2006-09-16)
Fifteen years have passed since the cloning and characterization of the interleukin-1beta-converting enzyme (ICE/caspase-1), the first identified member of a family of proteases currently known as caspases. Caspase-1 is the prototypical member of a subclass of caspases involved in cytokine
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