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SAB4503974

Sigma-Aldrich

Anti-phospho-PLK1 (pThr210) antibody produced in rabbit

affinity isolated antibody

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100 μG
₹40,015.50

₹40,015.50

Estimated to ship on30 June 2025Details

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100 μG
₹40,015.50

About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

₹40,015.50

Estimated to ship on30 June 2025Details

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 68 kDa

species reactivity

human, mouse, rat

concentration

~1 mg/mL

technique(s)

ELISA: 1:1000
immunohistochemistry: 1:50-1:100

NCBI accession no.

P53350

UniProt accession no.

P53350

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pThr210)

Gene Information

human ... PLK1(5347)

Related Categories

General description

Human polo-like kinase 1 (PLK1) is a serine/threonine kinase, that is located on human chromosome 16p12.

Immunogen

The antiserum was produced against synthesized peptide derived from human PLK1 around the phosphorylation site of Thr210.

Immunogen Range: 176-225

Biochem/physiol Actions

Polo-like kinase 1 (PLK1) plays an important role in the functional maturation of mitotic centrosomes. It actively participates in the development of the cell cycle. This gene is considered as an important therapeutic target as it is overexpressed in several cancer types.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
110554

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Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes
H A Lane and E A Nigg
The Journal of Cell Biology, 1701-1713 (1996)
Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1
Petronczki M, et al.
Developmental Cell, 14(5), 646-659 (2008)
Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors
Kolberg M, et al.
Molecular Oncology, 11(9), 1156-1171 (2017)

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