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About This Item
Empirical Formula (Hill Notation):
C76H104N18O20S2
CAS Number:
Molecular Weight:
1653.88
MDL number:
UNSPSC Code:
12352200
Assay
≥90% (HPLC)
storage temp.
−20°C
SMILES string
CC(N)C(=O)NCC(=O)NC1CSSCC(NC(=O)C(CO)NC(=O)C(NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(Cc3c[nH]c4ccccc34)NC(=O)C(Cc5ccccc5)NC(=O)C(Cc6ccccc6)NC(=O)C(CC(N)=O)NC(=O)C(CCCCN)NC1=O)C(C)O)C(C)O)C(O)=O
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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K Yoshida et al.
Gastroenterologia Japonica, 24(6), 611-618 (1989-12-01)
To investigate the mechanism of the suppressive action of somatostatin on gastric acid secretion, we determined the somatostatin binding and adenylate cyclase activity on crude membrane fractions of isolated gastric glands of guinea pigs. The binding studies using 125I-Tyr11 somatostatin
S López-Sañudo et al.
Brain research, 614(1-2), 171-177 (1993-06-18)
DL-Propranolol (PRO), a beta-adrenergic blocking agent, and the neuropeptide somatostatin (SS) have central nervous system depressant and anticonvulsive properties. To investigate a possible relationship between these two components, we studied the influence of PRO and DL-isoproterenol (ISO), a beta-adrenergic agonist
F Reyl-Desmars et al.
The Journal of biological chemistry, 264(31), 18789-18795 (1989-11-05)
The human gastric tumoral cell line HGT-1 was previously shown to contain a membrane somatostatin receptor negatively coupled to adenylate cyclase through a pertussis toxin-sensitive inhibitory GTP-binding regulatory protein (Gi) (Reyl-Desmars, F., Laboisse, C., and Lewin, M. J. M. (1986)
J A Koenig et al.
British journal of pharmacology, 120(1), 45-51 (1997-01-01)
1. We have used somatostatin (SRIF) receptor subtype-selective ligands to determine some of the operational characteristics of somatostatin receptors in Neuro2A mouse neuroblastoma cells. The potent SRIF1-receptor selective ligand, BIM-23027, was able to displace completely the specific binding of radioiodinated
S J Sullivan et al.
Endocrinology, 121(2), 544-552 (1987-08-01)
Somatostatin (SRIF) is a neuropeptide which inhibits secretion from a variety of target cells including pancreatic beta-cells. In this study we have used the RINm5F rat insulinoma cell line to characterize high affinity receptors for SRIF. The binding of 0.03
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