S3388

Sulforhodamine 101 acid chloride

Technical grade

• Synonym(s): Sulforhodamine 101 sulfonyl chloride
• Empirical Formula (Hill Notation): C₃₁H₂₉ClN₂O₆S₂
• CAS Number: 82354-19-6
• Molecular Weight: 625.15
• Beilstein: 8667894
• MDL number: MFCD00012406
• UNSPSC Code: 12171500
• PubChem Substance ID: 24899558
• NACRES: NA.47

Properties

• form: powder
• composition: Dye content, ~75%
• impurities: ~1 mol/mol chloroform as solvent of crystallization
• solubility: methanol: 10 mg/mL
• fluorescence: λ_ex 586 nm; λ_em 605 nm in H₂O
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: −20°C
• SMILES string: [O-]S(=O)(=O)c1cc(ccc1C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)S(Cl)(=O)=O
• InChI: 1S/C31H29ClN2O6S2/c32-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-33-13-3-7-22(28(18)33)30(24)40-31-23-8-4-14-34-12-2-6-19(29(23)34)16-25(27)31/h9-10,15-17H,1-8,11-14H2
• InChI key: MPLHNVLQVRSVEE-UHFFFAOYSA-N

Description

General description

Sulforhodamine 101 is a red fluorescent dye. It is water-soluble, amphoteric rhodamine. The dye can be specifically used as a marker of astroglia in the neocortex. It is commonly used for brain imaging. Studies suggest that sulforhodamine 101 may be used as an epileptogenic agent.

Application

Sulforhodamine 101 acid chloride has been used in an encapsulated fluorescent probe as a model drug to study drug-delivery properties of rhamnogalacturonan-I based microcapsules. It has also been used in confocal imaging as an astrocyte specific dye.

Linkage

Mixture of the two monosulfonyl chloride derivatives of sulforhodamine 101.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H315,H319,H351,H361d,H372
• Precautionary Statements: P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable