O5889

Opipramol dihydrochloride

≥98% (HPLC), solid

• Synonym(s): 4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol dihydrochloride
• Empirical Formula (Hill Notation): C₂₃H₂₉N₃O · 2HCl
• CAS Number: 909-39-7
• Molecular Weight: 436.42
• EC Number: 213-000-2
• MDL number: MFCD00941483
• UNSPSC Code: 12352200
• PubChem Substance ID: 24724565
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• color: yellow
• solubility: H₂O: ~24 mg/mL
• SMILES string: Cl[H].Cl[H].OCCN1CCN(CCCN2c3ccccc3C=Cc4ccccc24)CC1
• InChI: 1S/C23H29N3O.2ClH/c27-19-18-25-16-14-24(15-17-25)12-5-13-26-22-8-3-1-6-20(22)10-11-21-7-2-4-9-23(21)26;;/h1-4,6-11,27H,5,12-19H2;2*1H
• InChI key: DLTOEESOSYKJBK-UHFFFAOYSA-N

Description

General description

Opipramol acts as an antidepressant and is chemically similar to tricyclic antidepressants. It is an atypical anxiolytic and antidepressant drug. Opipramol mainly acts on sigma receptors. It is usually found to be much effective in depressive disorder. It has the ability to prevent histamine, serotonin, dopamine and alpha-1 adrenergic receptors.

Biochem/physiol Actions

σ₁/σ₂ opioid receptor agonist; an antagonist at D₂, 5HT₂ and H₁ receptors; atypical antidepressant, antipsychotic and anxiolytic

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302,H410
• Precautionary Statements: P264 - P270 - P273 - P301 + P312 - P391 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable