M3763

Adenosine 5′-(α,β-methylene)diphosphate

ADP analog

• Synonym(s): α,β-Methyleneadenosine 5′-diphosphate, ADP[α,β-CH₂], AMP-CP
• Empirical Formula (Hill Notation): C₁₁H₁₇N₅O₉P₂
• CAS Number: 3768-14-7
• Molecular Weight: 425.23
• Beilstein: 633678
• EC Number: 223-194-0
• MDL number: MFCD00042991
• UNSPSC Code: 41106305
• PubChem Substance ID: 24896872
• NACRES: NA.51

Properties

• biological source: synthetic (organic)
• Assay: ≥99% (HPLC)
• form: powder
• solubility: water: 50 mg/mL, clear, colorless
• storage temp.: −20°C
• SMILES string: Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]3O
• InChI: 1S/C11H17N5O9P2/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(25-11)1-24-27(22,23)4-26(19,20)21/h2-3,5,7-8,11,17-18H,1,4H2,(H,22,23)(H2,12,13,14)(H2,19,20,21)/t5-,7-,8-,11-/m1/s1
• InChI key: OLCWZBFDIYXLAA-IOSLPCCCSA-N

Description

Application

Adenosine 5′-(α,β-methylene)diphosphate has been used as a component of culture media, to study its effects as an inhibitor of cluster of differentiation 73 (CD73) and adenosinergic signaling regulation via CD73 or ecto-5′-nucleotidase.

Reconstitution

soluble in water up to Approx. 50 mg/ml with heating

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves