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H4511

Sigma-Aldrich

Serotonin hydrogen maleate

powder

Synonym(s):

3-(2-Aminoethyl)-5-hydroxyindole hydrogen maleate, 5-HT, 5-Hydroxytryptamine hydrogen maleate

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About This Item

Empirical Formula (Hill Notation):
C10H12N2O · C4H4O4
CAS Number:
18525-25-2
Molecular Weight:
292.29
Beilstein:
8173182
EC Number:
242-399-6
MDL number:
MFCD00043256
UNSPSC Code:
12352200
PubChem Substance ID:
24895516

form

powder

color

off-white to yellow

storage temp.

2-8°C

SMILES string

OC(=O)\C=C/C(O)=O.NCCc1c[nH]c2ccc(O)cc12

InChI

1S/C10H12N2O.C4H4O4/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;5-3(6)1-2-4(7)8/h1-2,5-6,12-13H,3-4,11H2;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

LTEXAUVYLLADEB-BTJKTKAUSA-N

Gene Information

human ... HTR3A(3359)

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Biochem/physiol Actions

Neurotransmitter.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBG7182V
BCBC9666V
BCBC9666
1417202
1429718

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Kerry L Price et al.
ACS chemical neuroscience, 6(7), 1151-1157 (2015-02-05)
Cys-loop receptors are the site of action of many therapeutic drugs. One of these is the smoking cessation agent varenicline, which has its major therapeutic effects at nicotinic acetylcholine (nACh) receptors but also acts at 5-HT3 receptors. Here, we report
Jason Neidleman et al.
Cell reports. Medicine, 1(6), 100081-100081 (2020-08-26)
Convalescing coronavirus disease 2019 (COVID-19) patients mount robust T cell responses against SARS-CoV-2, suggesting an important role of T cells in viral clearance. To date, the phenotypes of SARS-CoV-2-specific T cells remain poorly defined. Using 38-parameter CyTOF, we phenotyped longitudinal specimens of SARS-CoV-2-specific
Jason Neidleman et al.
Cell reports, 36(3), 109414-109414 (2021-07-15)
Although T cells are likely players in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity, little is known about the phenotypic features of SARS-CoV-2-specific T cells associated with recovery from severe coronavirus disease 2019 (COVID-19). We analyze T cells from 34 individuals with
Nicolas Kluger et al.
Clinical immunology (Orlando, Fla.), 158(2), 212-220 (2015-03-26)
Gastrointestinal dysfunction is a disabling manifestation of APECED possibly related to an autoimmune intestinal aggression. We evaluated its features in a cohort of 31 Finnish patients. The most frequent manifestations were constipation (48%), diarrhea, dysphagia and retrosternal pain (45%). AADC
Di Wang et al.
Journal of neurophysiology, 112(1), 30-38 (2014-04-18)
The lamprey central nervous system has been used extensively as a model system for investigating the networks underlying vertebrate motor behavior. The locomotor networks can be activated by application of glutamate agonists, such as N-methyl-D-aspartic acid (NMDA), to the isolated
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