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About This Item
Empirical Formula (Hill Notation):
C24H26N2O6
CAS Number:
Molecular Weight:
438.47
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
storage temp.
−20°C
SMILES string
COC(=O)C(=O)N1CCC[C@@H]1C(=O)N[C@H](Cc2ccccc2)C(=O)OCc3ccccc3
Biochem/physiol Actions
Inhibits binding of the envelope protein (gp120) of the HIV-1 virus to the cell surface glycoprotein CD4.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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R W Finberg et al.
Science (New York, N.Y.), 249(4966), 287-291 (1990-07-20)
Infection by human immunodeficiency virus type-1 (HIV-1) is initiated when its envelope protein, gp120, binds to its receptor, the cell surface glycoprotein CD4. Small molecules, termed N-carbomethoxycarbonyl-prolyl-phenylalanyl benzyl esters (CPFs), blocked this binding. CPFs interacted with gp120 and did not
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