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A7766

Sigma-Aldrich

N4-Acetylcytidine

≥98%

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About This Item

Empirical Formula (Hill Notation):
C11H15N3O6
CAS Number:
Molecular Weight:
285.25
EC Number:
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
Pricing and availability is not currently available.

Assay

≥98%

mp

199 °C (dec.) (lit.)

storage temp.

−20°C

SMILES string

CC(=O)NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O

InChI

1S/C11H15N3O6/c1-5(16)12-7-2-3-14(11(19)13-7)10-9(18)8(17)6(4-15)20-10/h2-3,6,8-10,15,17-18H,4H2,1H3,(H,12,13,16,19)/t6-,8-,9-,10-/m1/s1

InChI key

NIDVTARKFBZMOT-PEBGCTIMSA-N

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G Kawai et al.
Nucleic acids symposium series, (21)(21), 61-62 (1989-01-01)
The conformational characteristics of a modified nucleoside 4-acetylcytidine (ac4C) was analyzed by proton nuclear magnetic resonance spectroscopy. This nucleoside was found to take the C3'-endo form predominantly. The enthalpy difference between the C2'-endo form and the C3'-endo form of the
Clement T Y Chan et al.
PLoS genetics, 6(12), e1001247-e1001247 (2010-12-29)
Decades of study have revealed more than 100 ribonucleoside structures incorporated as post-transcriptional modifications mainly in tRNA and rRNA, yet the larger functional dynamics of this conserved system are unclear. To this end, we developed a highly precise mass spectrometric
G S Morris et al.
Biomedical chromatography : BMC, 1(3), 109-118 (1986-06-01)
Inherited purine and pyrimidine disorders may be associated with serious, sometimes life-threatening consequences. Early and accurate diagnosis is essential. Difficulties encountered when using existing high pressure liquid chromatographic (HPLC) methods led to the development of an improved method based on
Wilson R Sinclair et al.
ACS chemical biology, 12(12), 2922-2926 (2017-10-19)
The human acetyltransferase NAT10 has recently been shown to catalyze formation of N4-acetylcytidine (ac4C), a minor nucleobase known to alter RNA structure and function. In order to better understand the role of RNA acetyltransferases in biology and disease, here we
Marcus J O Johansson et al.
RNA (New York, N.Y.), 10(4), 712-719 (2004-03-24)
The biogenesis of transfer RNA is a process that requires many different factors. In this study, we describe a genetic screen aimed to identify gene products participating in this process. By screening for mutations lethal in combination with a sup61-T47:2C

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