This substance is synthetic organic. The product has been offered previously before 2023. See below for an example of the Certificate of Origin.
https://www.sigmaaldrich.com/coo/undefined/A5752/SHBL7005
A5752
Adrenochrome
>95% purity (HPLC), powder
Synonym(s):
3-Hydroxy-1-methyl-5,6-indolinedione
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25 MG
₹8,291.95
250 MG
₹45,822.23
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25 MG
₹8,291.95
250 MG
₹45,822.23
About This Item
Empirical Formula (Hill Notation):
C9H9NO3
CAS Number:
Molecular Weight:
179.17
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
Recommended Products
Product Name
Adrenochrome, ≥95% (HPLC)
Quality Level
Assay
≥95% (HPLC)
form
powder
color
red to brown
εmax
3-4.5 at 485-490 nm in water
9.0-10.5 at 299-304 nm in water
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
−20°C
SMILES string
CN1CC(O)C2=CC(=O)C(=O)C=C12
InChI
1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3
InChI key
RPHLQSHHTJORHI-UHFFFAOYSA-N
Related Categories
Application
Adrenochrome has been used to study the effect of adrenochrome on coronary artery constriction in the rat heart.[1]
Biochem/physiol Actions
Adrenochrome is an oxidation product of adrenaline.[2] It has been implicated in cardiotoxicity.[3][4] It is a short-lived cytotoxic molecule and is part of the leukocyte response used to kill bacteria.[5] Adrenochrome is also suggested to exhibit psychotomimetic effects.[6] It is used to determine superoxide dismutase activity.[7]
related product
Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Viviana S Fluxá et al.
Nature protocols, 3(8), 1270-1277 (2008-08-21)
The adrenaline test for enzymes is a colorimetric enzyme assay based on the quantification of periodate-sensitive reaction products such as 1,2-diols and 1,2-aminoalcohols by back-titration of the oxidant with adrenaline to produce adrenochrome as an easily detectable red product. The
Adrenochrome-induced coronary artery constriction in the rat heart.
Karmazyn M, et al.
Journal of Pharmacology and Experimental Therapeutics, 219, 225-225 (1981)
Maria Luisa Genova et al.
Archives of biochemistry and biophysics, 447(2), 167-173 (2006-02-21)
Complex I in bovine heart submitochondrial particles catalyses the NADH-supported generation of superoxide anion; adrenaline is oxidised by superoxide to adrenochrome that, on its hand, is reduced by Complex I, thus establishing a redox cycle that amplifies the superoxide production.
Janna Shainsky et al.
Applied and environmental microbiology, 75(14), 4711-4719 (2009-05-26)
Enantiopure sulfoxides are prevalent in drugs and are useful chiral auxiliaries in organic synthesis. The biocatalytic enantioselective oxidation of prochiral sulfides is a direct and economical approach for the synthesis of optically pure sulfoxides. The selection of suitable biocatalysts requires
The oxidative metabolism of catecholamines in the brain: a review.
Smythies J and Galzigna L
Biochimica et Biophysica Acta, 1380, 159-159 (1998)
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Is this substance synthetic or naturally derived? Some download able Data on this product is dated 1/16/2023. Is this a relatively new substance?
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