Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Y0000079

Articaine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester hydrochloride, Carticaine chlorhydrate, Carticaine hydrochloride

Sign Into View Organizational & Contract Pricing

Select a Size

200 MG
₹14,072.50

₹14,072.50

Estimated to ship on13 March 2025Details

Request a Bulk Order
All Photos(1)

Select a Size

Change View
200 MG
₹14,072.50

About This Item

Empirical Formula (Hill Notation):
C13H20N2O3S · HCl
CAS Number:
23964-57-0
Molecular Weight:
320.84
MDL number:
MFCD00190157
UNSPSC Code:
41116107
PubChem Substance ID:
329830834
NACRES:
NA.24

₹14,072.50

Estimated to ship on13 March 2025Details

Request a Bulk Order

grade

pharmaceutical primary standard

API family

articaine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC1=CSC(C(OC)=O)=C1NC(C(C)NCCC)=O.Cl

InChI

1S/C13H20N2O3S.ClH/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)18-4;/h7,9,14H,5-6H2,1-4H3,(H,15,16);1H

InChI key

GDWDBGSWGNEMGJ-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Articaine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Articaine is an amide local anesthetic widely used in dentistry. Articaine acts by inhibition of nerve impulse conduction by blockade of sodium channels.
Articaine is an amide local anesthetic; sodium channel blocker.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Y0000081

Articaine impurity E, European Pharmacopoeia (EP) Reference Standard

1042918

Articaine hydrochloride, United States Pharmacopeia (USP) Reference Standard

1042907

Articaine, United States Pharmacopeia (USP) Reference Standard

1042929

Articaine Related Compound A, United States Pharmacopeia (USP) Reference Standard

1042930

Articaine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1042962

Articaine Related Compound E, United States Pharmacopeia (USP) Reference Standard

PHR1882

Articaine, Pharmaceutical Secondary Standard; Certified Reference Material

07356

4-Methyl-N-propyl-3-[[(2RS)-2-(propylamino)propanoyl]amino]thiophene-2-carboxamide hydrochloride, reference material

07380

1-Methylethyl 4-methyl-3-[[(2RS)-2-(propylamino)-propanoyl]amino]thiophene-2-carboxylate hydrochloride, reference material

CRM69760

Methyl 3-[[(2RS)-2-bromopropanoyl]amino]-4-methylthiophene-2-carboxylate, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

CRM72531

Methyl 3-[[(2RS)-2-(ethylamino)propanoyl]amino]-4-methylthiophene-2- carboxylate hydrochloride, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Local anesthetics.
W Braden Speer
Journal of the American Dental Association (1939), 144(1), 17-17 (2013-01-04)
Khalid E El-Kholey
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 71(10), 1658-1658 (2013-09-18)
Profound anesthesia for mandibular molars by buccal infiltration has been tried in recent years, with promising results. This prospective, randomized, single-blinded, crossover study investigated the clinical anesthetic efficacy obtained with 1:100,000 epinephrine plus 4% articaine (A100) 1.8 versus 3.6 mL
Hengameh Ashraf et al.
Journal of endodontics, 39(1), 6-10 (2012-12-12)
Profound pulpal anesthesia in posterior mandibular teeth with irreversible pulpitis usually requires administering an inferior alveolar nerve block (IANB) plus other supplemental injections. The purpose of this prospective, randomized, double-blind study was to compare the anesthetic success rate of buccal
Gabriel A Sánchez et al.
Acta odontologica latinoamericana : AOL, 25(1), 34-39 (2012-08-30)
Local anesthetics used in dentistry have myotoxic effects. Articaine, also known as carticaine, is one of the local anesthetics most widely used in clinical dentistry. The aim of this work was to describe its effect on the sarcoplasmic reticulum Ca-ATPase
Anna Smothers Dressman et al.
Journal of endodontics, 39(3), 313-318 (2013-02-14)
The authors conducted a prospective, randomized, single-blind study to determine the degree of pulpal anesthesia obtained with a primary infiltration of 1 cartridge of articaine in the incisive/mental nerve region of the mandibular second premolar and to determine the anesthetic
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service