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SMB00968

Sigma-Aldrich

Steroid Standard Mixture

suitable for mass spectrometry (MS)

Synonym(s):

Deuterated Steroids Standard mixture, Steroids mixture

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About This Item

UNSPSC Code:
12352211
NACRES:
NA.28

form

liquid

Quality Level

100

technique(s)

mass spectrometry (MS): suitable

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

Related Categories

General description

Steroid hormones are essential in numerous physiological processes including metabolism, homeostasis, development, growth, reproduction and energy metabolism. They also have profound roles in molecular and cellular mechanisms. Thus, an accurate quantitative or qualitative analysis is required for research purposes. This can be achieved by using stable isotope labeled steroid standards.

Application

A method of choice for target or untargeted metabolomics analysis of different classes of steroid′s is Liquid Chromatography – Mass Spectrometry (LC-MS). For targeted or untargeted metabolomics overcoming ion suppression, ion variability and drifting signal are challenging aspects of analysis. Use of a deuterated steroids mixture could overcome those challenges.

Features and Benefits

Steroids standard mixture is dissolved in methanol. This mixture product is formulated for use as a concentration standard for high-throughput LC/MS metabolomic analysis.

  • All deuterated steroids are dissolved in methanol and ready to use. Total vial volume is 1 ml.
  • This mixture can be used for targeted and untargeted approaches.
  • Ideal for LC-MS studies as internal standards.

Analyte

Description
    Aldosterone-d7
    11-Deoxycortisol-d5
    Androstenedione-c3
    Aldosterone-d8
    Corticosterone-d4
    Allopregnanolone-d5
    Hydrocortisone Sulfate-d4
    Cortisone-d8
    Testosterone-d3
    Cortisol-d4
    5α-Dihydrotestosterone-d3
    Progesterone-d9
    17-OH progesterone-d8
    Dehydroepiandrosterone-d6 sulfate sodium salt
    See All (14)

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 1 - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

51.8 °F

Flash Point(C)

11 °C

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Certificates of Analysis (COA)

Lot/Batch Number
SLCP9806

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Dinesh K Barupal et al.
Metabolites, 9(5) (2019-05-28)
Mouse knockouts facilitate the study ofgene functions. Often, multiple abnormal phenotypes are induced when a gene is inactivated. The International Mouse Phenotyping Consortium (IMPC) has generated thousands of mouse knockouts and catalogued their phenotype data. We have acquired metabolomics data

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