Skip to Content
Merck
All Photos(4)

Documents

A8251

Sigma-Aldrich

Acriflavine hydrochloride

Powder

Synonym(s):

3,6-Diamino-10-methylacridinium chloride hydrochloride, Euflavine

Sign Into View Organizational & Contract Pricing
All Photos(4)

About This Item

CAS Number:
8063-24-9
Beilstein:
6265525
MDL number:
MFCD00069039
UNSPSC Code:
12171500
PubChem Substance ID:
24891216
NACRES:
NA.47

product name

Acriflavine hydrochloride, fluorescent dye

Quality Level

200

form

powder

composition

Acriflavine HCL content, 10-50%
Proflavine HCL, 25-70%

color

faint brown to brown, and Orange to Dark Orange and Red to Very Dark Red

mp

260 °C (dec.) (lit.)

solubility

H2O: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Cl-].Cl[H].Cl[H].Nc1ccc2cc3ccc(N)cc3nc2c1.C[n+]4c5cc(N)ccc5cc6ccc(N)cc46

InChI

1S/C14H13N3.C13H11N3.3ClH/c1-17-13-7-11(15)4-2-9(13)6-10-3-5-12(16)8-14(10)17;14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;;;/h2-8H,1H3,(H3,15,16);1-7H,14-15H2;3*1H

InChI key

MKLTXAHQKDVBLY-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

In living mice, acriflavine hydrochloride has been used in the confocal laser endomicroscopy to check the crypt structure in mucosa. It has also been used in Neurospora strain selection by checking the acriflavine resistance.

Biochem/physiol Actions

Acriflavine hydrochloride is a fluorescent dye. It is used as a topical contrast agent. It mainly stains nuclei and is applied to tissues before microscopy.

Other Notes

A mixture of 3,6-diamino-10-methylacridinium (acriflavin) and 3,6-diaminoacridine (proflavin)

Signal Word

Danger

Hazard Statements

H302,H318,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SHBR5332
SHBR8114
SHBR3518
SHBM0542
SHBQ3710

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Confocal endomicroscopy: in vivo diagnosis of neoplastic lesions of the gastrointestinal tract.
Goetz M and Kiesslich R
Anticancer Research, 28, 353-360 (2008)
Yang Hua et al.
Journal of AOAC International, 95(6), 1672-1688 (2013-03-05)
The Roka Listeria Detection Assay was compared to the reference culture methods for nine select foods and three select surfaces. The Roka method used Half-Fraser Broth for enrichment at 35 +/- 2 degrees C for 24-28 h. Comparison of Roka's
Nashwa Amin et al.
Cells, 10(6) (2021-07-03)
Hypoxia-inducible factor 1 can sufficiently control the progress of neurological symptoms after ischemic stroke owing to their actions associated with its downstream genes. In this study, we evaluated the role of HIF-1α in attenuating brain damage after endothelin-1 injection. Focal
Confocal laser endomicroscopy and narrow-band imaging-aided endoscopy for in vivo imaging of colitis and colon cancer in mice.
Waldner MJ, et al.
Nature Protocols, 6, 1471-1481 (2011)
Jian Yang et al.
Journal of the American Heart Association, 7(5) (2018-02-27)
Limb remote ischemic preconditioning (RIPC) protects against brain injury induced by stroke, but the underlying protective mechanisms remain unknown. As hypoxia inducible factor 1α (HIF-1α) is neuroprotective in stroke and mediates neuroinflammation, we tested the hypothesis that HIF-1α is a
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service