Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

A115

Supelco

Amitriptyline metabolite, (±)-E-10-hydroxylated-

analytical standard

Synonym(s):

(±)-(E)-5-[3-(Dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol

Sign Into View Organizational & Contract Pricing

Select a Size

2 MG
₹29,238.33

₹29,238.33

Please contact Customer Service for Availability
Request a Bulk Order
All Photos(1)

Select a Size

Change View
2 MG
₹29,238.33

About This Item

Empirical Formula (Hill Notation):
C20H23NO
CAS Number:
64520-05-4
Molecular Weight:
293.40
MDL number:
MFCD00069200
UNSPSC Code:
41116107
PubChem Substance ID:
329770681
NACRES:
NA.24

₹29,238.33

Please contact Customer Service for Availability
Request a Bulk Order

grade

analytical standard

Quality Level

200

form

solid

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white

mp

97-99 °C

solubility

0.1 M HCl: soluble
H2O: insoluble
methanol: soluble

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CN(C)CC\C=C1/c2ccccc2CC(O)c3ccccc13

InChI

1S/C20H23NO/c1-21(2)13-7-12-17-16-9-4-3-8-15(16)14-20(22)19-11-6-5-10-18(17)19/h3-6,8-12,20,22H,7,13-14H2,1-2H3/b17-12+

InChI key

GHWBJXOKAFHZAI-SFQUDFHCSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Metabolite of amitriptyline, tricyclic antidepressant; chromatographic standard.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

X Zhang
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 25(4), 196-198 (1992-08-01)
The serum concentrations of amitriptyline and its 3 metabolites--nortriptyline, 10-hydroxy-amitriptyline and 10-hydroxy-nortriptyline were determined in 18 depressive patients treated with amitriptyline for 6 weeks. The relationships between the serum concentrations and the clinical effects were statistically analyzed and showed significant
U Breyer-Pfaff et al.
Clinical pharmacology and therapeutics, 52(4), 350-358 (1992-10-01)
In 26 hospitalized patients with depression, a combined pharmacogenetic test with dextromethorphan, a substrate of cytochrome P450IID6, and mephenytoin, the S-form of which is hydroxylated by a P450IIC isozyme, was carried out before amitriptyline therapy. Metabolites were determined in 24-hour
F Coudoré et al.
Fundamental & clinical pharmacology, 8(6), 525-531 (1994-01-01)
Kinetics of amitriptyline (AMI), its demethylated metabolites nortriptyline (NOR) and demethylnortriptyline (DM-NOR), and its hydroxylated metabolites, the E and Z isomers or 10-hydroxy-amitriptyline (E- and Z-10-OH-AMI) and of 10-hydroxynortriptyline (E- and Z-10-OH-NOR) were studied in plasma and brain from Swiss
K Shimoda et al.
Journal of clinical psychopharmacology, 15(3), 175-181 (1995-06-01)
We measured the concentrations in plasma of amitriptyline and its metabolites, nortriptyline and geometric isomers of 10-hydroxynortriptyline and 10-hydroxyamitriptyline, in 73 Japanese psychiatric patients receiving amitriptyline hydrochloride (Tryptanol; Banyu Pharmaceutical Co. Ltd., Tokyo, Japan) by high-performance liquid chromatography. Although there
P Baumann et al.
International clinical psychopharmacology, 1(2), 102-112 (1986-04-01)
A subgroup of 16 out of 30 endogenous depressive inpatients (cf. part I), treated for 3 weeks with 150 mg amitriptyline (AT) daily, participated in a pharmacogenetic study: all were phenotyped with debrisoquine and 3 of them with mephenytoin. Four
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service