The toxic effects of 2-bromopropane (2-BP) on the reproductive tracts of male F1 offspring from dams exposed to 2-BP during gestation and lactation were investigated. Ten pregnant (sperm-positive) Sprague-Dawley rats per group were exposed sc to 2-BP at 135, 405
Journal of toxicology and environmental health. Part A, 65(5-6), 383-394 (2002-04-09)
Immunotoxic effects of 2-bromopropane were investigated in male Sprague-Dawley rats. The rats were treated orally daily with 2-bromopropane at 100, 330, or 1000 mg/kg for 28 consecutive days. Four days before necropsy, the rats were immunized intravenously with sheep red
Archives of pharmacal research, 25(1), 39-44 (2002-03-12)
Recently, we have reported that 2-bromopropane might have an immunotoxic potential in rats when exposed for 28 days. In the present studies, the possibility of 2i-deoxyguanosine adduct formation by 2-bromopropane was investigated in vitro to elucidate molecular mechanism of 2-bromopropane-induced
2-Bromopropane (2-BP) was used as an alternative for ozone-depleting solvents, which caused reproductive disorders in male workers and laboratory animals. A recent study indicated that 2-BP impaired antioxidant cellular defences and enhanced lipid peroxidation (LPO). Melatonin is a powerful endogenous
Wei sheng yan jiu = Journal of hygiene research, 39(1), 4-8 (2010-04-07)
To study the reproductive toxicity of male rats exposed to 1-bromopropane and 2-bromopropane and to explore the toxic mechanism of two isomers. 18 SPF SD male rats were randomly divided into 3 groups of 6 each, respectively. The groups were
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