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23514

Sigma-Aldrich

2-Chloro-1,3,2-benzodioxaphosphorin-4-one

purum, ≥95.0% (AT)

Synonym(s):

Salicyl chlorophosphite

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About This Item

Empirical Formula (Hill Notation):
C7H4ClO3P
CAS Number:
Molecular Weight:
202.53
Beilstein:
1311951
MDL number:
UNSPSC Code:
12350000
PubChem Substance ID:

grade

purum

Assay

≥95.0% (AT)

bp

127-128 °C/11 mmHg (lit.)

mp

36-40 °C (lit.)

storage temp.

2-8°C

SMILES string

ClP1OC(=O)c2ccccc2O1

InChI

1S/C7H4ClO3P/c8-12-10-6-4-2-1-3-5(6)7(9)11-12/h1-4H

InChI key

BVOITXUNGDUXRW-UHFFFAOYSA-N

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Other Notes

Phosphitylating agent for nucleosides and carbohydrates; Synthesis of triphosphates and 1-thiotriphosphates from alcohols

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J.P.G. Hermans et al.
Rec. Trav. Chim., 105, 510-510 (1986)
Yuka Kato et al.
Nucleic acids research, 33(9), 2942-2951 (2005-05-26)
The synthesis of the triphosphates of 4'-thiouridine and 4'-thiocytidine, 4'-thioUTP (7; thioUTP) and 4'-thioCTP (8; thioCTP), and their utility for SELEX (systematic evolution of ligands by exponential enrichment) is described. The new nucleoside triphosphate (NTP) analogs 7 and 8 were
J.E. Marugg et al.
Tetrahedron Letters, 27, 2661-2661 (1986)
P. Westerduin et al.
Tetrahedron Letters, 27, 6271-6271 (1986)

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