Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

22695

Sigma-Aldrich

8-Quinolinesulfonyl chloride

≥96.0% (AT)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C9H6ClNO2S
CAS Number:
18704-37-5
Molecular Weight:
227.67
Beilstein:
156347
EC Number:
242-515-5
MDL number:
MFCD00006808
UNSPSC Code:
12352100
PubChem Substance ID:
329752337

Quality Level

100

Assay

≥96.0% (AT)

form

solid

mp

126-129 °C (lit.)
126-129 °C

solubility

methanol: soluble 10 mg/mL, clear, colorless to light yellow

SMILES string

ClS(=O)(=O)c1cccc2cccnc12

InChI

1S/C9H6ClNO2S/c10-14(12,13)8-5-1-3-7-4-2-6-11-9(7)8/h1-6H

InChI key

JUYUYCIJACTHMK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

8-Quinolinesulfonyl chloride reacts with aromatic/heterocyclic sulfonamides containing a free amino, imino, hydrazino or hydroxyl group to form water-soluble compounds[1].

Application

8-Quinolinesulfonyl chloride was used as a coupling reagent in oligonucleotide synthesis[2][3][4]. It was also used in the synthesis of olefins from secondary esters at moderate temperature[5]

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

E.J. Corey et al.
The Journal of Organic Chemistry, 54, 389-389 (1989)
H. Takaku et al.
The Journal of Organic Chemistry, 48, 1399-1399 (1983)
H. Takaku et al.
The Journal of Organic Chemistry, 46, 589-589 (1981)
H. Takaku et al.
The Journal of Organic Chemistry, 45, 3347-3347 (1980)
J Borras et al.
Bioorganic & medicinal chemistry, 7(11), 2397-2406 (2000-01-13)
Reaction of 20 aromatic/heterocyclic sulfonamides containing a free amino, imino, hydrazino or hydroxyl group, with 8-quinoline-sulfonyl chloride afforded a series of water-soluble (as hydrochloride or triflate salts) compounds. The new derivatives were assayed as inhibitors of the zinc enzyme carbonic
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service