18-1010
L-Leucine
SAJ special grade, ≥99.0%
Synonym(s):
(S)-2-Amino-4-methylpentanoic acid
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About This Item
Linear Formula:
(CH3)2CHCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
131.17
Beilstein:
1721722
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
Pricing and availability is not currently available.
Recommended Products
grade
SAJ special grade
Assay
≥99.0%
availability
available only in Japan
mp
>300 °C (lit.)
application(s)
peptide synthesis
SMILES string
CC(C)C[C@H](N)C(O)=O
InChI
1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
InChI key
ROHFNLRQFUQHCH-YFKPBYRVSA-N
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Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Sebastian Kalamajski et al.
Matrix biology : journal of the International Society for Matrix Biology, 29(4), 248-253 (2010-01-19)
Small leucine-rich proteoglycans/proteins (SLRPs) are associated with collagen fibril formation, and therefore important for the proper formation of extracellular matrices. SLRPs are differentially expressed in tissues and during pathological conditions, contributing to the development of connective tissue properties. The binding
Qian Wang et al.
Journal of the National Cancer Institute, 105(19), 1463-1473 (2013-09-21)
L-type amino acid transporters (LATs) uptake neutral amino acids including L-leucine into cells, stimulating mammalian target of rapamycin complex 1 signaling and protein synthesis. LAT1 and LAT3 are overexpressed at different stages of prostate cancer, and they are responsible for
M Sakamoto et al.
The Journal of clinical endocrinology and metabolism, 56(1), 202-204 (1983-01-01)
Recent studies on the nucleotide sequence of cloned DNA complementary to mRNA for preproenkephalin from bovine adrenal medulla and human pheochromocytoma have revealed that this precursor molecule contains four copies of methionine-enkephalin (Met-Enk) and one copy each of leucine-enkephalin (Leu-Enk)
T Yoshimasa et al.
The Journal of clinical investigation, 69(3), 643-650 (1982-03-01)
To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with
Gaetano Santulli et al.
The Journal of clinical investigation, 125(5), 1968-1978 (2015-04-07)
The type 2 ryanodine receptor (RyR2) is a Ca2+ release channel on the endoplasmic reticulum (ER) of several types of cells, including cardiomyocytes and pancreatic β cells. In cardiomyocytes, RyR2-dependent Ca2+ release is critical for excitation-contraction coupling; however, a functional
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