The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. KLHL1 contains one BTB (POZ) domain and six Klech repoeats. KLHL1 may play an important role in organizing the actin cytoskeleton of the brain cells. Mutations associated with KLHL1 are inplicated in spinocerebellar ataxia type 8 (SCA8).
Immunogen
KLH-conjugated linear peptide corresponding to human KLHL1.
Application
Detect Kelch-like 1 using this rabbit polyclonal antibody, Anti-KLHL1 Antibody validated for use in western blotting & IHC.
Immunohistochemistry Analysis: 10 µg/mL from a representative lot detected KLHL1 in rat brain tissue.
Research Category Cell Structure
Research Sub Category Cytoskeleton
Quality
Evaluated by Western Blotting in human brain tissue lysate.
Western Blotting Analysis: 4 µg/mL of this antibody detected KLHL1 in 15 µg/mL of human brain tissue lysate.
Target description
~100 kDa observed
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control Human brain tissue lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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