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ABN38

Sigma-Aldrich

Anti-RAB35 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Ras-related protein Rab-35, GTP-binding protein RAY, Ras-related protein Rab-1C

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, human, horse

species reactivity (predicted by homology)

canine (based on 100% sequence homology), equine (based on 100% sequence homology)

technique(s)

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI accession no.

NP_006852

UniProt accession no.

Q15286

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... RAB35(11021)

General description

RAB35 is a member of the Rab GTPases identified in the human genome. It is ubiquitously expressed and regulates a fast endocytotic recycling events associated with the terminal steps of cytokinesis, the formation of immunological synapse, and peptide loading onto major histocompatibility complex III molecules. RAB35 also plays a significant role in the formation of the immunological synapse (IS) between peptide-loaded antigen presenting cells (APCs) and T cells.

Specificity

This antibody recognizes RAB35 at the C-terminus.

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminus of human RAB35.

Application

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected RAB35 in normal human brain tissue.
This Anti-RAB35 Antibody is validated for use in WB, IH(P) for the detection of RAB35.

Quality

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected RAB35 on 10 µg of human brain tissue lysate.

Target description

~19 kDa observed. The calculated molecular weight is 23 kDa

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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