Age-related maculopathy susceptibility protein 2 (ARMS2) is highly expressed in the human placenta and retina. The biological function of ARMS2 has not been fully characterized. However, previous studies have linked mutations in the ARMS2 and HtrA1 genes, located on chromosome 10q26, to the occurrence of age-related macular degeneration type 8, a condition of irreversible vision loss in the elderly.
Immunogen
GST-tagged recombinant protein corresponding to human ARMS2.
Application
Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected ARMS2 in human placenta tissue.
Research Category Neuroscience
Research Sub Category Developmental Signaling
This Anti-ARMS2 Antibody is validated for use in Immunohistochemistry (Paraffin) for the detection of ARMS2.
Quality
Evaluated by Immunohistochemistry in human retina tissue.
Immunohistochemistry Analysis: A 1:2,000 dilution of this antibody detected ARMS2 in human retina tissue.
Target description
15 kDa calculated
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Other Notes
Concentration: Please refer to lot specific datasheet.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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