614005

Tobramycin, Free Base

Aminoglycoside antibiotic active against Gram negative bacteria. Inhibits myeloperoxidase-dependent oxidant cell injury.

• Synonym(s): Tobramycin, Free Base
• Empirical Formula (Hill Notation): C₁₈H₃₇N₅O₉
• CAS Number: 32986-56-4
• Molecular Weight: 467.51
• MDL number: MFCD00077885
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated
• color: white to off-white
• solubility: water: soluble
• shipped in: ambient
• storage temp.: 10-30°C
• InChI: 1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1
• InChI key: NLVFBUXFDBBNBW-PBSUHMDJSA-N

Description

General description

Aminoglycoside antibiotic active against Gram negative bacteria. Inhibits myeloperoxidase-dependent oxidant cell injury.

Aminoglycoside antibiotic. Inhibits myeloperoxidase-dependent oxidant cell injury.

Biochem/physiol Actions

Primary Target
myeloperoxidase-dependent oxidant cell injury

Warning

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Other Notes

Cantin, A. and Woods, D.E. 1993. J. Clin. Invest. 91, 38.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H361f
• Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3