A nitric oxide (NO) donor. A stable NO-amine complex that can release two equivalents of NO spontaneously in solution under physiological conditions without a cofactor. Half-life (t½) of NO release is 93 min (PBS, pH 7.4, 22°C).
A nitric oxide (NO) donor. A stable NO-amine complex that can spontaneously release two equivalents of NO in solution under physiological conditions without any cofactor. Half-life (t½) in PBS, pH 7.4 is 93 minutes at 22°C. Relatively stable in alkaline solution (pH ≥10.0).
Biochem/physiol Actions
Cell permeable: no
Primary Target A nitric oxide (NO) donor
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Irritant (B)
Reconstitution
Following reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O just prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.
Other Notes
Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
5.2 - Organic peroxides and self-reacting hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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