D100706

Diethyl sulfate

98%

• Synonym(s): Ethyl sulfate, Sulfuric acid diethyl ester
• Linear Formula: (C₂H₅O)₂SO₂
• CAS Number: 64-67-5
• Molecular Weight: 154.18
• Beilstein: 1209714
• EC Number: 200-589-6
• MDL number: MFCD00009099
• UNSPSC Code: 12352108
• PubChem Substance ID: 24893316
• NACRES: NA.22

Properties

• vapor density: 5.3 (vs air)
• Quality Level: 200
• vapor pressure: <0.01 mmHg ( 20 °C); 2 mmHg ( 55 °C)
• Assay: 98%
• form: liquid
• refractive index: n20/D 1.399 (lit.)
• bp: 208 °C (lit.)
• mp: −24 °C (lit.)
• density: 1.177 g/mL at 25 °C (lit.)
• SMILES string: CCOS(=O)(=O)OCC
• InChI: 1S/C4H10O4S/c1-3-7-9(5,6)8-4-2/h3-4H2,1-2H3
• InChI key: DENRZWYUOJLTMF-UHFFFAOYSA-N

Description

Application

Diethyl sulfate can be used as a reactant for the synthesis of:

• Biologically active compounds such as bispyrazole, pyrazolopyrimidine and pyridine containing antipyrinyl moieties.
• N-substituted-2-styryl-4(3H)-quinazolinones.
• Ionic liquids with pyrrolidinium, piperidinium and morpholinium cations, having potential applications as electrolytes.

It can also be used as an alkylating agent to synthesize 1-alkyl/aralkyl-2-(1-arylsufonylalkyl)benzimidazoles and an ionic liquid ethylmethylimidazole ethylsulfate ([EMIM][EtSO₄].

Safety Information

• Pictograms: GHS08,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302 + H312 + H332,H314,H340,H350
• Precautionary Statements: P202 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Muta. 1B - Skin Corr. 1B
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 219.2 °F - closed cup
• Flash Point(C): 104 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves