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Key Documents

925926

Sigma-Aldrich

Methacrylated Silk Fibroin

Synonym(s):

SilMA, Silk fibroin

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About This Item

CAS Number:
96690-41-4
MDL number:
MFCD28359009
UNSPSC Code:
12162002
NACRES:
NA.23
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description

Degree of substitution ~20%

Quality Level

100

form

(Powder or sponge)

mol wt

average mol wt >10000

impurities

≤0.5% hybrid protein content (m/m)
≤0.5% total carbohydrate (m/m)
≤10 μg/mL heavy metal content

color

white to off-white

pH

6-7 ( in water)

storage temp.

−20°C

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Application

Silk is a natural polymer composed of two proteins - fibroin and sericin. Silk fibroin has been widely used in biomedical applications due to its biocompatibility and biodegradability. Silk Methacryloyl (SilMA) is produced by methacrylation of silk fibroin using glycidyl methacrylate. The hydrogels prepared using SilMA possesse superior mechanical strength and rheological properties, which make them ideal for tissue engineering applications. SilMA can be used for bioink formulation. And SilMA bioinks are suitable for use in digital light processing (DLP) based 3D bioprinting to develop functional tissue constructs.

Packaging

1 g in glass bottle

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW0951
MKCR6890

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Digital light processing 3D printed silk fibroin hydrogel for cartilage tissue engineering
Hong H, et al.
BMC Medicine, 119679-119679 (2020)
Precisely printable and biocompatible silk fibroin bioink for digital light processing 3D printing
Kim, S.H, et al.
Natural computing, 1620-1620 (2018)

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