771228

2,4-Difluorophenylboronic acid MIDA ester

97%

• Synonym(s): 2-(2,4-Difluorophenyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione
• Empirical Formula (Hill Notation): C₁₁H₁₀BF₂NO₄
• Molecular Weight: 269.01
• MDL number: MFCD26142776
• UNSPSC Code: 12352103
• PubChem Substance ID: 329767479
• NACRES: NA.22

Properties

• Assay: 97%
• form: solid
• mp: 199-201 °C
• SMILES string: O=C(CN(C)C1)OB(C2=C(F)C=C(F)C=C2)OC1=O
• InChI: 1S/C11H10BF2NO4/c1-15-5-10(16)18-12(19-11(17)6-15)8-3-2-7(13)4-9(8)14/h2-4H,5-6H2,1H3
• InChI key: AFNQHENRIQSJMU-UHFFFAOYSA-N

Description

Application

Protected boronic acid with methylimindodiacetic acid (MIDA) that does not react under standard Suzuki-Miyuara coupling conditions, allowing for selective and iterative cross-coupling sequences. The MIDA boronate also provides prolonged shelf life and stability to typically unstable boronic acid derivatives.

MIDA Boronates

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable