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742023

Sigma-Aldrich

Gold nanoparticles

80 nm diameter, OD 1, stabilized suspension in citrate buffer

Synonym(s):

Au NP, Gold Colloid

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25 ML
₹11,732.70
100 ML
₹30,214.20

₹11,732.70


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25 ML
₹11,732.70
100 ML
₹30,214.20

About This Item

MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.23

₹11,732.70


Please contact Customer Service for Availability

Request a Bulk Order

Quality Level

form

nanoparticles
suspension

contains

Proprietary Surfactant as stabilizer

concentration

~7.8E+9 particles/mL

OD

1

diameter

80 nm

λmax

550-557 nm

PDI

<0.2

storage temp.

2-8°C

SMILES string

[Au]

InChI

1S/Au

InChI key

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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Application

Ideal for adsorption of thiolated ligands such as oligonucleotides and polyethylene glycols. Also, due to the increased stability, these gold nanoparticles are ideal for use in physical and optical applications. Note: This product is not ideal for protein adsorption. For gold nanoparticles suitable for adsorption of proteins and other ligands for conjugate development, please see our gold nanoparticles stabilized in PBS.

This material is highly monodisperse (<12% variability in size and shape), and provides significantly improved surface reactivity. Applications include Surface Enhanced Raman Lables, Sensing/Detection, Biological Targeting, Plasmonics and Electronics.

Legal Information

Product of CytoDiagnostics, Inc.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Takayuki Umakoshi et al.
Biochimica et biophysica acta. General subjects, 1864(2), 129325-129325 (2019-03-21)
High-speed atomic force microscopy (HS-AFM) has successfully visualized a variety of protein molecules during their functional activity. However, it cannot visualize small molecules interacting with proteins and even protein molecules when they are encapsulated. Thus, it has been desired to

Articles

Steven J. Oldenburg, Ph.D. provides an overview of lateral flow diagnostic assays and discusses the use of ultra-bright reporter particles based on the unique optical properties of gold nanoshells that significantly increase the sensitivity of lateral flow immunoassays.

Gold (Au) nanoparticles have tunable optical and electronic properties and are used in a number of applications including photovoltaics, sensors, drug delivery & catalysis.

Silver nanomaterials have unique physical, chemical, and optical properties that are currently being leveraged for a wide variety of biological applications.

The diversity of applications and nanostructured materials accessible using ultrasonic spray methods are highlighted in this article.

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Questions

1–10 of 11 Questions  
  1. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  2. How do you attach gold nanoparticles to glass?

    1 answer
    1. To view the procedure on how to attach gold nanoparticles to glass please view information in the reference - Journal of Atomic, Molecular, and Optical PhysicsVolume 2012 (2012). Article ID 683830, 6 pagesdoi:10.1155/2012/683830

      Helpful?

  3. Do I need to wash my gold nanoparticles?

    1 answer
    1. For most applications, our gold nanoparticles can be used without any additional washing steps. If you have a sensitive application that requires additional washing the best way to do so is by either centrifugation or filtration.

      Helpful?

  4. My gold nanoparticles settle out of solution upon storage. Is this normal?

    1 answer
    1. Settling of gold nanoparticles on the bottom of the storage flask is completely normal and is especially common for larger sized particles, which settles at greater speed. Settling does not affect the performance of the particles. Prior to use, simply swirl the solution to properly disperse your gold nanoparticles and obtain a homogenous solution.

      Helpful?

  5. What is the shape of the gold nanoparticles?

    1 answer
    1. The majority (>95%) of the gold nanoparticles are spherical.

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  6. Can the Gold nanoparticles be frozen?

    1 answer
    1. No, the Gold nanoparticles should not be frozen.  If frozen, the gold nanoparticles will irreversibly aggregate, turning the solution clear.

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  7. How do you attach gold nanoparticles to peptides and peptide conjugates?

    1 answer
    1. To view information on how to attach gold nanoparticles to peptides and peptide conjugates, please view the information in the reference - Rosenthal, S. J. and Wright, D. W. (Eds.). (2005), p. 91-92. NanoBiotechnology Protocols. New Jersey. Humana Press.

      Helpful?

  8. How do you attach gold nanoparticles to oligos?

    1 answer
    1. To attach gold nanoparticles to oligos please view the information in the attached reference - Bioconjug Chem. 2011 Apr 20;22(4):794-807. Epub 2011 Mar 28.

      Helpful?

  9. Which gold nanoparticle size should I choose for my application?

    1 answer
    1. The size of gold nanoparticle to use is very depandent upon the intended application. Generally, smaller particles offer better sensitivity in applications such as immunogold labeling due to less steric hindrance and the ability to bind more gold nanoparticles to the desired target. Small gold nanoparticles are less visible than larger particles, however, which must also be taken into account.As an application example, particles with a size between 30-50nm are particularly useful for the development of rapid tests such as lateral flow assays.

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  10. How does the storage temperature relate to shipping conditions?

    1 answer
    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

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1–10 of 11 Questions  

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