[reaction: see text] A facile procedure for the incorporation of N-methyl phenothiazine as the terminal nucleoside in oligodeoxynucleotides is reported. The phenothiazine nucleoside analogue is synthesized and then incorporated into DNA using an automated DNA solid-phase synthesizer. Phenothiazine-labeled oligodeoxynucleotides form
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 63(2), 349-360 (2005-06-23)
In this work the authors deal with the vibrational spectroscopy of three derivatives of phenothiazine: the 10-methyl-10H-phenothiazine, the 10 methyl-10H-phenothiazine-3-carbaldehyde and the 10-methyl-10H-phenothiazine-3-yl-methanol. The authors investigated the vibrational spectroscopic behaviour of the phenothiazine skeleton and dealt with the aldehyde and
Phenothiazine can be incorporated as a redox-active probe into DNA in two conceptually different ways: the non-nucleosidic DNA base surrogate exhibits similar properties to 10-methylphenothiazine but with no preferential base-pairing properties, whereas the phenothiazine-modified uridine has different optical and electrochemical
The electro-controlled delivery of drugs based on the doping-dedoping mechanism of Electro-Conducting Polymers is restricted to charged substances acting as dopants. In order to overcome this limitation, this study presents an approach where the trapping/delivering is based on host-guest interaction.
Yao xue xue bao = Acta pharmaceutica Sinica, 43(3), 291-294 (2008-07-17)
The electrocatalytic oxidation of glutathione (reduced form GSH) at 10-methylphenothiazine (MPT) modified carbon paste electrode (MPT/CPE) was investigated by cyclic voltammetry (CV). Although GSH itself showed a very poor electrochemical response at carbon paste electrode (CPE), the response could be
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