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Key Documents

420174

Sigma-Aldrich

cis-3-Hydroxy-DL-proline

95%

Synonym(s):

(±)-cis-3-Hydroxypyrrolidine-2-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C5H9NO3
CAS Number:
Molecular Weight:
131.13
Beilstein:
4130229
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

Assay

95%

reaction suitability

reaction type: solution phase peptide synthesis

mp

232 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

O[C@@H]1CCN[C@@H]1C(O)=O

InChI

1S/C5H9NO3/c7-3-1-2-6-4(3)5(8)9/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1

InChI key

BJBUEDPLEOHJGE-DMTCNVIQSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Identification of 3-hydroxyproline residues in several proteins of Fasciola hepatica.
S E Bozas et al.
Experimental parasitology, 82(1), 69-72 (1996-01-01)
Sanjay Morzaria et al.
The Journal of otolaryngology, 34(5), 297-303 (2005-09-27)
To develop an evidence-based algorithm for determining the etiology of bilateral sensorineural hearing loss (SNHL) in a child. The frequency of different etiologies was previously determined. A systematic review of the literature for articles published between 1940 and January 2003
Mary Ann Weis et al.
The Journal of biological chemistry, 285(4), 2580-2590 (2009-11-27)
Collagen triple helices are stabilized by 4-hydroxyproline residues. No function is known for the much less common 3-hydroxyproline (3Hyp), although genetic defects inhibiting its formation cause recessive osteogenesis imperfecta. To help understand the pathogenesis, we used mass spectrometry to identify
B Bartosch et al.
Archives of disease in childhood, 66(2), 248-251 (1991-02-01)
Alport's syndrome is characterised by morphological and structural changes of the renal basement membranes. As the hydroxyproline content of isolated glomerular basement membranes is reduced in patients with Alport's syndrome, it is possible that the renal excretion of 3-hydroxproline (3-OHP)
Improved method for the evaluation of 3-hydroxyproline and 4-hydroxyproline in the urine.
G Bellon et al.
Journal of chromatography, 230(2), 420-426 (1982-07-09)

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