Brown adipose tissue (BAT) has been identified as a promising target for the treatment of obesity, diabetes, and relevant metabolism disorders because of the adaptive thermogenesis ability of this tissue. Visualizing BAT may provide an essential tool for pathology study
Fluorescence image-guided surgery combined with intraoperative therapeutic modalities has great potential for intraoperative detection of oncologic targets and eradication of unresectable cancer residues. Therefore, we have developed an activatable theranostic nanoplatform that can be used concurrently for two purposes: (1)
Journal of photochemistry and photobiology. B, Biology, 42(3), 202-210 (1998-05-22)
The photosensitizing activity of the new far-red absorbing naphthalocyanine SiNc [OSi (n-C10H21)3] [OSi(CH3)2(CH2)3N(CH3)2], (DAP-SiNc), and of its analogue SiNc [OSi(i-C4H9)2(n-C18H37)]2, (IsoBO-SiNc), was studied with two cell variants of B16 melanoma, the amelanotic clone B78H1 and the highly pigmented B16F1 cells.
A water-soluble derivative of the highly hydrophobic molecule Si(IV)-naphthalocyanine was synthesized by the addition of two polyethyleneglycol ligands in axial positions to the centrally coordinated Si(IV) ion. The compound can be intravenously injected in homogeneous aqueous solution, where it is
Recently scanning probe microscopy has made tremendous progress in imaging organic molecules with high lateral resolution. Atoms and bonds within individual molecules have been clearly resolved, indicating the exciting potential of this technique for studying molecular structures, bonding within and
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
