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Sigma-Aldrich

Fmoc-Phe-OH

98%, for peptide synthesis

Synonym(s):

N-(9-Fluorenylmethoxycarbonyl)-L-phenylalanine, Fmoc-L-phenylalanine

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About This Item

Empirical Formula (Hill Notation):
C24H21NO4
CAS Number:
35661-40-6
Molecular Weight:
387.43
Beilstein:
3597808
EC Number:
252-661-1
MDL number:
MFCD00037128
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24860536
NACRES:
NA.26

product name

Fmoc-Phe-OH, 98%

Assay

98%

optical activity

[α]20/D −37°, c = 1 in DMF

reaction suitability

reaction type: C-H Activation
reaction type: Fmoc solid-phase peptide synthesis
reagent type: ligand
reaction type: Peptide Synthesis

mp

180-187 °C (lit.)

application(s)

peptide synthesis

functional group

Fmoc
amine
carboxylic acid

storage temp.

2-8°C

SMILES string

OC(=O)[C@H](Cc1ccccc1)NC(=O)OCC2c3ccccc3-c4ccccc24

InChI

1S/C24H21NO4/c26-23(27)22(14-16-8-2-1-3-9-16)25-24(28)29-15-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-13,21-22H,14-15H2,(H,25,28)(H,26,27)/t22-/m0/s1

InChI key

SJVFAHZPLIXNDH-QFIPXVFZSA-N

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Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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The clearance of host cell proteins (HCPs) is of crucial importance in biomanufacturing, given their diversity in composition, structure, abundance, and occasional structural homology with the product. The current approach to HCP clearance in the manufacturing of monoclonal antibodies (mAbs)
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European journal of medicinal chemistry, 44(5), 1933-1940 (2008-12-27)
Twenty-four new dipeptide analogs (1-24) of aurantiamide acetate were designed, synthesized, and assayed for effects on superoxide anion generation and elastase release by human neutrophils in response to fMLP/CB. Among them, seven N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides (6, 9, 12, 14, 17, 18
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