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143936

Sigma-Aldrich

Propionamide

97%

Synonym(s):

Propanamide, Propylamide

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About This Item

Linear Formula:
CH3CH2CONH2
CAS Number:
Molecular Weight:
73.09
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

bp

213 °C (lit.)

mp

76-79 °C (lit.)

solubility

alcohol: freely soluble
chloroform: freely soluble
diethyl ether: freely soluble
water: freely soluble

density

1.042 g/mL at 25 °C (lit.)

SMILES string

CCC(N)=O

InChI

1S/C3H7NO/c1-2-3(4)5/h2H2,1H3,(H2,4,5)

InChI key

QLNJFJADRCOGBJ-UHFFFAOYSA-N

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General description

Propionamide on γ-irradiation reacts with sulfur dioxide and this reaction has been studied by ESR spectroscopy, gas absorption measurements and X-ray diffraction.

Application

Propionamide was used as adsorbent in the determination of adsorption isotherms of acetamide and propionamide on multi-wall carbon nanotube. It was used in a robust screening method to study biotransformations using (+)-γ-lactamase enzyme.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Study of Adsorption Isotherms of Acetamide and Propionamide on Carbon Nanotube.
Vadi M and Moradi N.
Orient. J. Chem., 27(4), 1491-1491 (2011)
Reactions of Gases with Irradiated Organic Solids: III. Reactions of Propionamide, n-Butyramide, Isobutyramide, Methacrylamide, Valeramide, and Stearamide with Sulfur Dioxide.
Perotti A, et al.
Mol. Cryst. Liq. Cryst., 9(1), 323-342 (2969)
Nobuhito Yukuhiro et al.
Brain research, 1027(1-2), 59-66 (2004-10-21)
We investigated the effects of (S)-N-[2-(1,6,7,8-tetrahydro-2H-indeno-[5,4]furan-8-yl)ethyl]propionamide (ramelteon, TAK-375), a novel MT1/MT2 receptor agonist, on nocturnal sleep in freely moving monkeys and compared these results with those of melatonin and zolpidem. Treatment with ramelteon (0.03 and 0.3 mg/kg, p.o.) significantly shortened
David Crich et al.
The Journal of organic chemistry, 74(9), 3389-3393 (2009-04-25)
Beta-thiolactones monosubstituted in the 3-position by alkyl and carbamoyl groups undergo nucleophilic ring opening by arenethiolates through a process involving an S(N)2-type attack at the 4-position leading to 3-arylthiopropionates substituted in the 2-position. These thiocarboxylates can be trapped in situ
Tiia Kuuranne et al.
Drug metabolism and disposition: the biological fate of chemicals, 36(3), 571-581 (2007-12-19)
Selective androgen receptor modulators (SARM) are a prominent group of compounds for being misused in sports owing to their advantageous anabolic properties and reduced side effects. To target the preventive doping control analysis in relevant compounds, the challenge is to

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