1565009

Procarbazine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): N-(1-Methylethyl)-4-[(2-methylhydrazinyl)methyl]benzamide hydrochloride
• Empirical Formula (Hill Notation): C₁₂H₁₉N₃O·HCl
• CAS Number: 366-70-1
• Molecular Weight: 257.76
• MDL number: MFCD00072082
• UNSPSC Code: 41116107
• PubChem Substance ID: 329750958
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: procarbazine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl.CNNCc1ccc(cc1)C(=O)NC(C)C
• InChI: 1S/C12H19N3O.ClH/c1-9(2)15-12(16)11-6-4-10(5-7-11)8-14-13-3;/h4-7,9,13-14H,8H2,1-3H3,(H,15,16);1H
• InChI key: DERJYEZSLHIUKF-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Procarbazine hydrochloride USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as:

• Procarbazine Hydrochloride Capsules

Biochem/physiol Actions

Procarbazine is an antineoplastic alkylating agent widely used in cancer chemotherapy in combination with other compounds. It has multiple mechanisms of action. Procarbazine inhibits protein, RNA and DNA synthesis in addition to being an alkylating agent.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H341,H350,H360
• Precautionary Statements: P201 - P280 - P301 + P312 + P330 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Repr. 1A
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable