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T3452

Toloxatone

≥98% (HPLC), solid

Synonym(s):

5-(Hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone, Humoryl

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Size/SKUAvailabilityPrice
10 mg
Please contact Customer Service for Availability
₪608.00
50 mg
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₪2,445.00

About This Item

Empirical Formula (Hill Notation):
C11H13NO3
CAS Number:
Molecular Weight:
207.23
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12161501
EC Number:
249-522-2
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated

₪608.00


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Quality Segment

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

solubility

DMSO: >10 mg/mL

storage temp.

2-8°C

SMILES string

Cc1cccc(c1)N2CC(CO)OC2=O

InChI

1S/C11H13NO3/c1-8-3-2-4-9(5-8)12-6-10(7-13)15-11(12)14/h2-5,10,13H,6-7H2,1H3

InChI key

MXUNKHLAEDCYJL-UHFFFAOYSA-N

Biochem/physiol Actions

Toloxatone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant.
Toloxatone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant. Toloxatone belongs to the aryloxazolidinones, a relatively new class of reversible monoamine oxidase A inhibitors (MAOI). Studies show that derivatives such as 3-aryloxazolidin-2-one (oxazolidinones), which are regularly used to treat gram positive infections, represent a new class of reversible as well as irreversible inhibitors for MAO-A and MAO-B enzymes that are able to inhibit protein synthesis and also used for neurodegenerative-type pathologies.

Preparation Note

Toloxatone is soluble in DMSO at a concentration that is greater than 10 mg/ml.

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SML0248SML1058S3944
form

solid

form

powder

form

powder

form

solid

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

protect from light

solubility

DMSO: >10 mg/mL

solubility

DMSO: ≥5 mg/mL

solubility

DMSO: 10 mg/mL, clear (warmed)

solubility

DMSO: ≥10 mg/mL, H2O: insoluble


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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